XB-ART-12015
Curr Biol
1999 Nov 04;921:R812-5. doi: 10.1016/s0960-9822(99)80497-7.
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Vertebrate development: Multiple phases to endoderm formation.
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Recent results support a two-step model for endoderm formation in amphibian embryos, in which endoderm is initially specified by localised maternal factors, including the transcription factor VegT, but is then maintained by extracellular signalling molecules of the transforming growth factor-beta family.
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Species referenced: Xenopus laevis
Genes referenced: vegt