XB-ART-11766
Neuropharmacology
1999 Dec 01;3812:1913-5. doi: 10.1016/s0028-3908(99)00109-4.
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MTSEA potentiates 5-HT3 receptors containing the nicotinic alpha4 subunit.
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In order to study the subunit composition of 5-HT3 receptors (5-HT3R), we report that (2-aminoethyl)methanethiosulfonate (MTSEA) can enhance the function of both nicotinic ACh receptors (nAChRs) comprised of alpha4/beta2 subunits, and heteromeric channels assembled from serotonin 5-HT3R and alpha4 nAChR subunits. MTSEA has no effect on homomeric 5-HT3 receptor channels.
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