Ontogenez 2000 Jan 01;311:14-20.

[The effects of exogenous actin-binding casein kinase injected into the oocytes and ova of the clawed toad].

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The effects of microinjections of exogenous casein kinase 2 on the structural organization of the maturing oocytes and eggs were studied in Xenopus laevis. Kinase inhibited the progesterone-stimulated oocyte maturation and induced dislocation of pigment granules. The morphological effect was shown to be dose-dependent. The results obtained are discussed in the light of the possible influence of casein kinase 2 on the organization of the cortical actin cytoskeleton through phosphorylation of actin-binding proteins.

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Species referenced: Xenopus laevis
Genes referenced: actl6a