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The cranial neural crest (CNC) explant assay was originally designed to assess the basic requirements for CNC migration in vitro. This protocol describes the key parameters of CNC explants in Xenopus laevis, with a focus on how to extirpate CNC cells and assay their migration in vitro. The protocol can be adapted according to the needs of the experimenter, some examples of which are discussed here.
Alfandari,
Integrin alpha5beta1 supports the migration of Xenopus cranial neural crest on fibronectin.
2003, Pubmed,
Xenbase
Alfandari,
Integrin alpha5beta1 supports the migration of Xenopus cranial neural crest on fibronectin.
2003,
Pubmed
,
Xenbase
Becker,
Cadherin-11 mediates contact inhibition of locomotion during Xenopus neural crest cell migration.
2013,
Pubmed
,
Xenbase
Carmona-Fontaine,
Contact inhibition of locomotion in vivo controls neural crest directional migration.
2008,
Pubmed
,
Xenbase
Cousin,
ADAM13 function is required in the 3 dimensional context of the embryo during cranial neural crest cell migration in Xenopus laevis.
2012,
Pubmed
,
Xenbase
Friedl,
Tuning Collective Cell Migration by Cell-Cell Junction Regulation.
2017,
Pubmed
Sadaghiani,
Neural crest development in the Xenopus laevis embryo, studied by interspecific transplantation and scanning electron microscopy.
1987,
Pubmed
,
Xenbase
Sater,
Induction of neuronal differentiation by planar signals in Xenopus embryos.
1993,
Pubmed
,
Xenbase
Theveneau,
Chase-and-run between adjacent cell populations promotes directional collective migration.
2013,
Pubmed
Theveneau,
Beads on the run: beads as alternative tools for chemotaxis assays.
2011,
Pubmed
,
Xenbase