Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Cell Mol Neurobiol
1993 Jun 01;133:271-8. doi: 10.1007/bf00733755.
Show Gene links
Show Anatomy links
Identification of a 7B2-derived tridecapeptide from bovine adrenal medulla chromaffin vesicles.
Sigafoos J
,
Chestnut WG
,
Merrill BM
,
Taylor LC
,
Diliberto EJ
,
Viveros OH
.
???displayArticle.abstract???
1. A novel tridecapeptide was isolated from extracts of bovine adrenal medulla chromaffin vesicles and the primary structure determined to be SVPHFSDEDKDPE. 2. This peptide is identical to the C termini of human and porcine 7B2 and is highly homologous to the same region of the mouse and Xenopus lavis protein. 3. In all these species the homologous peptide is preceded by a pair of lysine residues, a potential proteolytic processing site. 4. Ser6 is part of a well-conserved casein kinase II consensus phosphorylation sequence. Evidence for phosphorylation of this residue was obtained during Edman sequencing. 5. Thus, this novel adrenal medullary probably arises from the posttranslational processing of the bovine 7B2 protein.
Ayoubi,
The neuroendocrine polypeptide 7B2 is a precursor protein.
1990, Pubmed,
Xenbase
Ayoubi,
The neuroendocrine polypeptide 7B2 is a precursor protein.
1990,
Pubmed
,
Xenbase
Benjannet,
Chromogranin B (secretogranin I), a putative precursor of two novel pituitary peptides through processing at paired basic residues.
1987,
Pubmed
Benjannet,
GAWK, a novel human pituitary polypeptide: isolation, immunocytochemical localization and complete amino acid sequence.
1985,
Pubmed
Brayton,
Cloning, characterization, and sequence of a porcine cDNA encoding a secreted neuronal and endocrine protein.
1988,
Pubmed
Devereux,
A comprehensive set of sequence analysis programs for the VAX.
1984,
Pubmed
Diliberto,
Subcellualr distribution of protein carboxymethylase and its endogenous substrates in the adrenal medulla: possible role in excitation-secretion coupling.
1976,
Pubmed
Dockray,
Post-translational processing of the porcine gastrin precursor by phosphorylation of the COOH-terminal fragment.
1987,
Pubmed
Fischer-Colbrie,
Immunological characterization of secretory proteins of chromaffin granules: chromogranins A, chromogranins B, and enkephalin-containing peptides.
1985,
Pubmed
Fischer-Colbrie,
Bovine chromaffin granules: immunological studies with antisera against neuropeptide Y, [Met]enkephalin and bombesin.
1986,
Pubmed
Flanagan,
A novel 1745-dalton pyroglutamyl peptide derived from chromogranin B is in the bovine adrenomedullary chromaffin vesicle.
1990,
Pubmed
Girault,
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.
1989,
Pubmed
Hsi,
Isolation and NH2-terminal sequence of a novel porcine anterior pituitary polypeptide. Homology to proinsulin, secretin and Rous sarcoma virus transforming protein TVFV60.
1982,
Pubmed
Iacangelo,
The sequence of porcine chromogranin A messenger RNA demonstrates chromogranin A can serve as the precursor for the biologically active hormone, pancreastatin.
1988,
Pubmed
Iguchi,
Presence of the novel pituitary protein "7B2" in bovine chromaffin granules: possible co-release of 7B2 and catecholamine as induced by nicotine.
1987,
Pubmed
Konecki,
The primary structure of human chromogranin A and pancreastatin.
1987,
Pubmed
Lazure,
Processed forms of neuroendocrine proteins 7B2 and secretogranin II are found in porcine pituitary extracts.
1991,
Pubmed
Majane,
Neuropeptide Y in bovine adrenal glands: distribution and characterization.
1985,
Pubmed
Marcinkiewicz,
Two-dimensional immunoblotting analysis and immunocytochemical localization of the secretory polypeptide 7B2 in adrenal medulla.
1988,
Pubmed
Martens,
Cloning and sequence analysis of human pituitary cDNA encoding the novel polypeptide 7B2.
1988,
Pubmed
,
Xenbase
Martens,
The novel pituitary polypeptide 7B2 is a highly-conserved protein coexpressed with proopiomelanocortin.
1989,
Pubmed
,
Xenbase
Mbikay,
cDNA sequence of neuroendocrine protein 7B2 expressed in beta cell tumors of transgenic mice.
1989,
Pubmed
Meyer,
Sequence analysis of phosphoserine-containing peptides. Modification for picomolar sensitivity.
1986,
Pubmed
Paquet,
Immunological identification and sequence characterization of a peptide derived from the processing of neuroendocrine protein 7B2.
1991,
Pubmed
Pinna,
Casein kinase 2: an 'eminence grise' in cellular regulation?
1990,
Pubmed
Rosa,
Secretogranins I and II: two tyrosine-sulfated secretory proteins common to a variety of cells secreting peptides by the regulated pathway.
1985,
Pubmed
Rosa,
Purification of a sulfated secretory protein from the adenohypophysis. Immunochemical evidence that similar macromolecules are present in other glands.
1983,
Pubmed
Seidah,
Isolation and NH2-terminal sequence of a highly conserved human and porcine pituitary protein belonging to a new superfamily. Immunocytochemical localization in pars distalis and pars nervosa of the pituitary and in the supraoptic nucleus of the hypothalamus.
1983,
Pubmed
Sigafoos,
A novel tetradecapeptide isolated from bovine adrenal medulla chromaffin vesicles with strong homology to an internal sequence coded by the rat 1B1075 (Preprosecretogranin III) gene.
1991,
Pubmed
Smith,
A specific soluble protein from the catecholamine storage vesicles of bovine adrenal medulla. I. Purification and chemical characterization.
1967,
Pubmed
Smith,
Purification and properties of an acidic protein from chromaffin granules of bovine adrenal medulla.
1967,
Pubmed
Somogyi,
Chromogranin immunoreactivity in the central nervous system. Immunochemical characterisation, distribution and relationship to catecholamine and enkephalin pathways.
1984,
Pubmed
Tatemoto,
Pancreastatin, a novel pancreatic peptide that inhibits insulin secretion.
,
Pubmed
Udenfriend,
Biochemistry of the enkephalins and enkephalin-containing peptides.
1983,
Pubmed
Viveros,
Opiate-like materials in the adrenal medulla: evidence for storage and secretion with catecholamines.
1979,
Pubmed
Watkinson,
The isolation and chemical characterization of phosphorylated enkephalin-containing peptides from bovine adrenal medulla.
1989,
Pubmed