XB-ART-12906
Microbiol Mol Biol Rev
1999 Jun 01;632:446-56. doi: 10.1128/MMBR.63.2.446-456.1999.
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Cytoplasmic polyadenylation in development and beyond.
Richter JD
.
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Maternal mRNA translation is regulated in large part by cytoplasmic polyadenylation. This process, which occurs in both vertebrates and invertebrates, is essential for meiosis and body patterning. In spite of the evolutionary conservation of cytoplasmic polyadenylation, many of the cis elements and trans-acting factors appear to have some species specificity. With the recent isolation and cloning of factors involved in both poly(A) elongation and deadenylation, the underlying biochemistry of these reactions is beginning to be elucidated. In addition to early development, cytoplasmic polyadenylation is now known to occur in the adult brain, and there is circumstantial evidence that this process occurs at synapses, where it could mediate the long-lasting phase of long-term potentiation, which is probably the basis of learning and memory. Finally, there may be multiple mechanisms by which polyadenylation promotes translation. Important questions yet to be answered in the field of cytoplasmic polyadenylation are addressed.
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References [+] :
Andrésson,
The kinase Eg2 is a component of the Xenopus oocyte progesterone-activated signaling pathway.
1998, Pubmed,
Xenbase
Andrésson, The kinase Eg2 is a component of the Xenopus oocyte progesterone-activated signaling pathway. 1998, Pubmed , Xenbase
Audic, Postfertilization deadenylation of mRNAs in Xenopus laevis embryos is sufficient to cause their degradation at the blastula stage. 1997, Pubmed , Xenbase
Ballantyne, A dependent pathway of cytoplasmic polyadenylation reactions linked to cell cycle control by c-mos and CDK1 activation. 1997, Pubmed , Xenbase
Ballantyne, Poly (A) polymerases in the nucleus and cytoplasm of frog oocytes: dynamic changes during oocyte maturation and early development. 1995, Pubmed , Xenbase
Bally-Cuif, Characterization of the zebrafish Orb/CPEB-related RNA binding protein and localization of maternal components in the zebrafish oocyte. 1998, Pubmed , Xenbase
Barkoff, Meiotic maturation in Xenopus requires polyadenylation of multiple mRNAs. 1998, Pubmed , Xenbase
Bilger, Nuclear polyadenylation factors recognize cytoplasmic polyadenylation elements. 1994, Pubmed , Xenbase
Bouvet, The deadenylation conferred by the 3' untranslated region of a developmentally controlled mRNA in Xenopus embryos is switched to polyadenylation by deletion of a short sequence element. 1994, Pubmed , Xenbase
Bouvet, A role for transcription and FRGY2 in masking maternal mRNA within Xenopus oocytes. 1994, Pubmed , Xenbase
Chen, AU-rich elements: characterization and importance in mRNA degradation. 1995, Pubmed
Colgan, Inhibition of poly(A) polymerase requires p34cdc2/cyclin B phosphorylation of multiple consensus and non-consensus sites. 1998, Pubmed , Xenbase
Colgan, Cell-cycle related regulation of poly(A) polymerase by phosphorylation. 1996, Pubmed , Xenbase
Colgan, Mechanism and regulation of mRNA polyadenylation. 1997, Pubmed
Cooperstock, Control of mRNA stability and translation during Drosophila development. 1997, Pubmed
Crino, Molecular characterization of the dendritic growth cone: regulated mRNA transport and local protein synthesis. 1996, Pubmed
Curtis, Translational regulation in development. 1995, Pubmed
Dworkin, Mobilization of specific maternal RNA species into polysomes after fertilization in Xenopus laevis. 1985, Pubmed , Xenbase
Fox, Polyadenylation of maternal mRNA during oocyte maturation: poly(A) addition in vitro requires a regulated RNA binding activity and a poly(A) polymerase. 1992, Pubmed
Fox, Poly(A) addition during maturation of frog oocytes: distinct nuclear and cytoplasmic activities and regulation by the sequence UUUUUAU. 1989, Pubmed , Xenbase
Fox, Poly(A) removal during oocyte maturation: a default reaction selectively prevented by specific sequences in the 3' UTR of certain maternal mRNAs. 1990, Pubmed , Xenbase
Gavis, Translational regulation of nanos by RNA localization. 1994, Pubmed
Gebauer, Mouse cytoplasmic polyadenylylation element binding protein: an evolutionarily conserved protein that interacts with the cytoplasmic polyadenylylation elements of c-mos mRNA. 1996, Pubmed , Xenbase
Gebauer, Synthesis and function of Mos: the control switch of vertebrate oocyte meiosis. 1997, Pubmed , Xenbase
Gebauer, Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse. 1994, Pubmed
Gebauer, Cloning and characterization of a Xenopus poly(A) polymerase. 1995, Pubmed , Xenbase
Gillian-Daniel, Modifications of the 5' cap of mRNAs during Xenopus oocyte maturation: independence from changes in poly(A) length and impact on translation. 1998, Pubmed , Xenbase
Gilmartin, CPSF recognition of an HIV-1 mRNA 3'-processing enhancer: multiple sequence contacts involved in poly(A) site definition. 1995, Pubmed
Good, A conserved family of elav-like genes in vertebrates. 1995, Pubmed , Xenbase
Goodwin, Translational regulation of tra-2 by its 3' untranslated region controls sexual identity in C. elegans. 1993, Pubmed
Goodwin, Translational control of development in C. elegans. 1997, Pubmed
Gotoh, Initiation of Xenopus oocyte maturation by activation of the mitogen-activated protein kinase cascade. 1995, Pubmed , Xenbase
Gray, Control of translation initiation in animals. 1998, Pubmed
Hake, Specificity of RNA binding by CPEB: requirement for RNA recognition motifs and a novel zinc finger. 1998, Pubmed , Xenbase
Hake, CPEB is a specificity factor that mediates cytoplasmic polyadenylation during Xenopus oocyte maturation. 1994, Pubmed , Xenbase
Huarte, Transient translational silencing by reversible mRNA deadenylation. 1992, Pubmed
Hwang, Maid: a maternally transcribed novel gene encoding a potential negative regulator of bHLH proteins in the mouse egg and zygote. 1997, Pubmed
Irish, The Drosophila posterior-group gene nanos functions by repressing hunchback activity. 1989, Pubmed
Jan, Conservation of the C.elegans tra-2 3'UTR translational control. 1997, Pubmed
Kang, A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity. 1996, Pubmed
Kanki, Progression from meiosis I to meiosis II in Xenopus oocytes requires de novo translation of the mosxe protooncogene. 1991, Pubmed , Xenbase
Kim-Ha, Translational regulation of oskar mRNA by bruno, an ovarian RNA-binding protein, is essential. 1995, Pubmed
Kuge, Cytoplasmic 3' poly(A) addition induces 5' cap ribose methylation: implications for translational control of maternal mRNA. 1995, Pubmed , Xenbase
Kuge, Cap ribose methylation of c-mos mRNA stimulates translation and oocyte maturation in Xenopus laevis. 1998, Pubmed , Xenbase
Körner, Poly(A) tail shortening by a mammalian poly(A)-specific 3'-exoribonuclease. 1997, Pubmed
Körner, The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes. 1998, Pubmed , Xenbase
Legagneux, Substrate-specific regulation of RNA deadenylation in Xenopus embryo and activated egg extracts. 1995, Pubmed , Xenbase
Legagneux, Identification of RNA-binding proteins specific to Xenopus Eg maternal mRNAs: association with the portion of Eg2 mRNA that promotes deadenylation in embryos. 1992, Pubmed , Xenbase
Lieberfarb, Mutations that perturb poly(A)-dependent maternal mRNA activation block the initiation of development. 1996, Pubmed
Martin, Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storage. 1997, Pubmed
McCarthy, Posttranscriptional control of gene expression in yeast. 1998, Pubmed
McGrew, Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element. 1989, Pubmed , Xenbase
McGrew, Translational control by cytoplasmic polyadenylation during Xenopus oocyte maturation: characterization of cis and trans elements and regulation by cyclin/MPF. 1990, Pubmed , Xenbase
Murata, Binding of pumilio to maternal hunchback mRNA is required for posterior patterning in Drosophila embryos. 1995, Pubmed
Müller, The U7 snRNP and the hairpin binding protein: Key players in histone mRNA metabolism. 1997, Pubmed , Xenbase
Ohsugi, Expression and cell membrane localization of catenins during mouse preimplantation development. 1996, Pubmed
Osborne, Translational control by polyadenylation during early development. 1997, Pubmed , Xenbase
Paillard, EDEN and EDEN-BP, a cis element and an associated factor that mediate sequence-specific mRNA deadenylation in Xenopus embryos. 1998, Pubmed , Xenbase
Paris, Maturation-specific polyadenylation: in vitro activation by p34cdc2 and phosphorylation of a 58-kD CPE-binding protein. 1991, Pubmed , Xenbase
Paris, Maturation-specific polyadenylation and translational control: diversity of cytoplasmic polyadenylation elements, influence of poly(A) tail size, and formation of stable polyadenylation complexes. 1990, Pubmed , Xenbase
Paynton, Polyadenylation and deadenylation of maternal mRNAs during oocyte growth and maturation in the mouse. 1994, Pubmed , Xenbase
Robinow, The elav gene product of Drosophila, required in neurons, has three RNP consensus motifs. 1988, Pubmed
Rosenthal, Sequence-specific adenylations and deadenylations accompany changes in the translation of maternal messenger RNA after fertilization of Spisula oocytes. 1983, Pubmed
Sachs, Starting at the beginning, middle, and end: translation initiation in eukaryotes. 1997, Pubmed
Sagata, What does Mos do in oocytes and somatic cells? 1997, Pubmed , Xenbase
Sagata, The product of the mos proto-oncogene as a candidate "initiator" for oocyte maturation. 1989, Pubmed , Xenbase
Sallés, Coordinate initiation of Drosophila development by regulated polyadenylation of maternal messenger RNAs. 1994, Pubmed
Schisa, Cytoplasmic polyadenylation of Toll mRNA is required for dorsal-ventral patterning in Drosophila embryogenesis. 1998, Pubmed
Seydoux, Mechanisms of translational control in early development. 1996, Pubmed , Xenbase
Sheets, The 3'-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation. 1994, Pubmed , Xenbase
Sheets, Polyadenylation of c-mos mRNA as a control point in Xenopus meiotic maturation. 1995, Pubmed , Xenbase
Simon, Cytoplasmic polyadenylation of activin receptor mRNA and the control of pattern formation in Xenopus development. 1996, Pubmed , Xenbase
Simon, Translational control by poly(A) elongation during Xenopus development: differential repression and enhancement by a novel cytoplasmic polyadenylation element. 1992, Pubmed , Xenbase
Simon, Further analysis of cytoplasmic polyadenylation in Xenopus embryos and identification of embryonic cytoplasmic polyadenylation element-binding proteins. 1994, Pubmed , Xenbase
St Johnston, The origin of pattern and polarity in the Drosophila embryo. 1992, Pubmed
Stebbins-Boaz, Multiple sequence elements and a maternal mRNA product control cdk2 RNA polyadenylation and translation during early Xenopus development. 1994, Pubmed , Xenbase
Stebbins-Boaz, CPEB controls the cytoplasmic polyadenylation of cyclin, Cdk2 and c-mos mRNAs and is necessary for oocyte maturation in Xenopus. 1996, Pubmed , Xenbase
Stebbins-Boaz, Translational control during early development. 1997, Pubmed
Steward, mRNA localization in neurons: a multipurpose mechanism? 1997, Pubmed
Steward, Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus. 1982, Pubmed
Struhl, Differing strategies for organizing anterior and posterior body pattern in Drosophila embryos. 1989, Pubmed
Stutz, Masking, unmasking, and regulated polyadenylation cooperate in the translational control of a dormant mRNA in mouse oocytes. 1998, Pubmed
Stutz, In vivo antisense oligodeoxynucleotide mapping reveals masked regulatory elements in an mRNA dormant in mouse oocytes. 1997, Pubmed
Swiderski, Photocrosslinking of proteins to maternal mRNA in Xenopus oocytes. 1988, Pubmed , Xenbase
Taieb, On cyclins, oocytes, and eggs. 1997, Pubmed
Temeles, Transient polyadenylation of a maternal mRNA following fertilization of mouse eggs. 1997, Pubmed
Tiedge, Translational machinery in dendrites of hippocampal neurons in culture. 1996, Pubmed
Timchenko, Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy. 1996, Pubmed
Varnum, Maturation-specific deadenylation in Xenopus oocytes requires nuclear and cytoplasmic factors. 1992, Pubmed , Xenbase
Varnum, Deadenylation of maternal mRNAs during Xenopus oocyte maturation does not require specific cis-sequences: a default mechanism for translational control. 1990, Pubmed , Xenbase
Vassalli, Regulated polyadenylation controls mRNA translation during meiotic maturation of mouse oocytes. 1989, Pubmed
Verrotti, Evolutionary conservation of sequence elements controlling cytoplasmic polyadenylylation. 1996, Pubmed , Xenbase
Verrotti, Oocyte selection of mutations affecting cytoplasmic polyadenylation of maternal mRNAs. 1997, Pubmed , Xenbase
Voeltz, AUUUA sequences direct mRNA deadenylation uncoupled from decay during Xenopus early development. 1998, Pubmed , Xenbase
Wahle, The biochemistry of 3'-end cleavage and polyadenylation of messenger RNA precursors. 1992, Pubmed
Walker, The clam 3' UTR masking element-binding protein p82 is a member of the CPEB family. 1999, Pubmed , Xenbase
Webster, Translational repressor bruno plays multiple roles in development and is widely conserved. 1997, Pubmed
Wells, Circularization of mRNA by eukaryotic translation initiation factors. 1998, Pubmed
West, Isolation and characterization of two novel, cytoplasmically polyadenylated, oocyte-specific, mouse maternal RNAs. 1996, Pubmed , Xenbase
Wharton, RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos. 1991, Pubmed
Wormington, Overexpression of poly(A) binding protein prevents maturation-specific deadenylation and translational inactivation in Xenopus oocytes. 1996, Pubmed , Xenbase
Wreden, Nanos and pumilio establish embryonic polarity in Drosophila by promoting posterior deadenylation of hunchback mRNA. 1997, Pubmed
Wu, CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses. 1998, Pubmed , Xenbase
Wu, The 36-kilodalton embryonic-type cytoplasmic polyadenylation element-binding protein in Xenopus laevis is ElrA, a member of the ELAV family of RNA-binding proteins. 1997, Pubmed , Xenbase
Zelus, Expression of the poly(A)-binding protein during development of Xenopus laevis. 1989, Pubmed , Xenbase
Zhao, Complex alternative RNA processing generates an unexpected diversity of poly(A) polymerase isoforms. 1996, Pubmed , Xenbase
de Moor, The Mos pathway regulates cytoplasmic polyadenylation in Xenopus oocytes. 1997, Pubmed , Xenbase
de Moor, Cytoplasmic polyadenylation elements mediate masking and unmasking of cyclin B1 mRNA. 1999, Pubmed , Xenbase