Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-31376
Proc Natl Acad Sci U S A 1980 Jul 01;777:4147-51.
Show Gene links Show Anatomy links

Transcription of tRNA genes in vivo: single-stranded compared to double-stranded templates.

Cortese R , Harland R , Melton D .


???displayArticle.abstract???
The expression of cloned tRNA genes has been studied by injecting single-stranded and double-stranded DNA templates into Xenopus oocyte nuclei. In both forms the genes are faithfully transcribed after injection. Some single-stranded DNA is converted into double-stranded DNA in the oocyte nucleus. This conversion is necessary for the expression of the injected tRNA gene: no tRNA transcription is observed when DNA synthesis is inhibited. We conclude that single-stranded DNA does not serve as a template for faithful transcription of this gene in injected oocytes.

???displayArticle.pubmedLink??? 7001455
???displayArticle.pmcLink??? PMC349787



Genes referenced: mt-tr trna

References [+] :
Brown, High-fidelity transcription of 5S DNA injected into Xenopus oocytes. 1977, Pubmed, Xenbase