XB-ART-18872
EMBO J
1995 Dec 15;1424:6301-10. doi: 10.1002/j.1460-2075.1995.tb00320.x.
Show Gene links
Show Anatomy links
Cytoplasmic 3' poly(A) addition induces 5' cap ribose methylation: implications for translational control of maternal mRNA.
Kuge H
,
Richter JD
.
???displayArticle.abstract???
During the early development of many animal species, the expression of new genetic information is governed by selective translation of stored maternal mRNAs. In many cases, this translational activation requires cytoplasmic poly(A) elongation. However, how this modification at the 3' end of an mRNA stimulates translation from the 5' end is unknown. Here we show that cytoplasmic polyadenylation stimulates cap ribose methylation during progesterone-induced oocyte maturation in Xenopus laevis. Translational recruitment of a chimeric reporter mRNA that is controlled by cytoplasmic polyadenylation coincides temporally with cap ribose methylation during this period. In addition, the inhibition of cap ribose methylation by S-isobutyladenosine significantly reduces translational activation of a reporter mRNA without affecting the increase of general protein synthesis or polyadenylation during maturation. These results provide evidence for a functional interaction between the termini of an mRNA molecule and suggest that 2'-O-ribose cap methylation mediates the translational recruitment of maternal mRNA.
???displayArticle.pubmedLink??? 8557049
???displayArticle.pmcLink??? PMC394754
???displayArticle.link??? EMBO J
Species referenced: Xenopus laevis
References [+] :
Aviv,
Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.
1972, Pubmed
Aviv, Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. 1972, Pubmed
Ballantyne, Poly (A) polymerases in the nucleus and cytoplasm of frog oocytes: dynamic changes during oocyte maturation and early development. 1995, Pubmed , Xenbase
Barbosa, mRNA(nucleoside-2'-)-methyltransferase from vaccinia virus. Characteristics and substrate specificity. 1978, Pubmed
Berleth, The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo. 1988, Pubmed
Bilger, Nuclear polyadenylation factors recognize cytoplasmic polyadenylation elements. 1994, Pubmed , Xenbase
Both, Ribosome binding to reovirus mRNA in protein synthesis requires 5' terminal 7-methylguanosine. 1975, Pubmed
Caldwell, The role of cap methylation in the translational activation of stored maternal histone mRNA in sea urchin embryos. 1985, Pubmed
DeLeon, Most early-variant histone mRNA is contained in the pronucleus of sea urchin eggs. 1983, Pubmed
Dworkin, Mobilization of specific maternal RNA species into polysomes after fertilization in Xenopus laevis. 1985, Pubmed , Xenbase
Fox, Poly(A) addition during maturation of frog oocytes: distinct nuclear and cytoplasmic activities and regulation by the sequence UUUUUAU. 1989, Pubmed , Xenbase
Fu, Translational potentiation of messenger RNA with secondary structure in Xenopus. 1991, Pubmed , Xenbase
Furuichi, 5'-Terminal structure and mRNA stability. 1977, Pubmed , Xenbase
Furuichi, Blocked, methylated 5'-terminal sequence in avian sarcoma virus RNA. 1975, Pubmed
Galili, Role of the 3'-poly(A) sequence in translational regulation of mRNAs in Xenopus laevis oocytes. 1988, Pubmed , Xenbase
Gallie, The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency. 1991, Pubmed
Gebauer, Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse. 1994, Pubmed
Gebauer, Cloning and characterization of a Xenopus poly(A) polymerase. 1995, Pubmed , Xenbase
Gershon, Stimulation of poly(A) tail elongation by the VP39 subunit of the vaccinia virus-encoded poly(A) polymerase. 1993, Pubmed
Grossi de Sa, The poly(A)-binding protein facilitates in vitro translation of poly(A)-rich mRNA. 1988, Pubmed
Gurdon, Changes in somatic cell nuclei inserted into growing and maturing amphibian oocytes. 1968, Pubmed , Xenbase
Hake, CPEB is a specificity factor that mediates cytoplasmic polyadenylation during Xenopus oocyte maturation. 1994, Pubmed , Xenbase
Hamm, Monomethylated cap structures facilitate RNA export from the nucleus. 1990, Pubmed , Xenbase
Huarte, Meiotic maturation of mouse oocytes triggers the translation and polyadenylation of dormant tissue-type plasminogen activator mRNA. 1987, Pubmed
Hyman, Translational inactivation of ribosomal protein mRNAs during Xenopus oocyte maturation. 1988, Pubmed , Xenbase
Izaurralde, A nuclear cap binding protein complex involved in pre-mRNA splicing. 1994, Pubmed , Xenbase
Konarska, Recognition of cap structure in splicing in vitro of mRNA precursors. 1984, Pubmed
Krainer, Normal and mutant human beta-globin pre-mRNAs are faithfully and efficiently spliced in vitro. 1984, Pubmed
Krieg, In vitro RNA synthesis with SP6 RNA polymerase. 1987, Pubmed
Kuge, Maturation of Xenopus laevis oocyte by progesterone requires poly(A) tail elongation of mRNA. 1992, Pubmed , Xenbase
Laskey, Protein synthesis in oocytes of Xenopus laevis is not regulated by the supply of messenger RNA. 1977, Pubmed , Xenbase
Lee, The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. 1993, Pubmed
Legagneux, Identification of RNA-binding proteins specific to Xenopus Eg maternal mRNAs: association with the portion of Eg2 mRNA that promotes deadenylation in embryos. 1992, Pubmed , Xenbase
McGrew, Translational control by cytoplasmic polyadenylation during Xenopus oocyte maturation: characterization of cis and trans elements and regulation by cyclin/MPF. 1990, Pubmed , Xenbase
McGrew, Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element. 1989, Pubmed , Xenbase
Muhlrad, Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript. 1994, Pubmed
Munns, Antibody-nucleic acid complexes. Immunospecific recognition of 7-methylguanine- and N6-methyladenine-containing 5'-terminal oligonucleotides of mRNA. 1979, Pubmed
Murray, Cyclin synthesis drives the early embryonic cell cycle. 1989, Pubmed , Xenbase
Muthukrishnan, Influence of 5'-terminal cap structure on the initiation of translation of vaccinia virus mRNA. 1978, Pubmed
Muthukrishnan, 5'-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation. 1975, Pubmed
Neuhard, Ion-exchange thin-layer chromatography. 13. Resolution of complex nucleoside triphosphate mixtures. 1965, Pubmed
O'Connor, Kinetic and electrophoretic analysis of transmethylation reactions in intact Xenopus laevis oocytes. 1987, Pubmed , Xenbase
Palatnik, Translational control during early Dictyostelium development: possible involvement of poly(A) sequences. 1984, Pubmed
Paris, Poly(A) metabolism and polysomal recruitment of maternal mRNAs during early Xenopus development. 1990, Pubmed , Xenbase
Paris, Maturation-specific polyadenylation: in vitro activation by p34cdc2 and phosphorylation of a 58-kD CPE-binding protein. 1991, Pubmed , Xenbase
Paris, Maturation-specific polyadenylation and translational control: diversity of cytoplasmic polyadenylation elements, influence of poly(A) tail size, and formation of stable polyadenylation complexes. 1990, Pubmed , Xenbase
Plotch, A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription. 1981, Pubmed
Proweller, Efficient translation of poly(A)-deficient mRNAs in Saccharomyces cerevisiae. 1994, Pubmed
Richter, Differential capacity for translation and lack of competition between mRNAs that segregate to free and membrane-bound polysomes. 1981, Pubmed , Xenbase
Richter, Translational control during early development. 1991, Pubmed , Xenbase
Robert-Géro, Inhibition of virus-induced cell transformation by synthetic analogues of S-adenosyl homocysteine. 1975, Pubmed
Rosenthal, Sequence-specific adenylations and deadenylations accompany changes in the translation of maternal messenger RNA after fertilization of Spisula oocytes. 1983, Pubmed
Sachs, Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast. 1992, Pubmed
Sachs, A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability. 1987, Pubmed
Sachs, The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation. 1989, Pubmed
Sagata, Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes. 1988, Pubmed , Xenbase
Sallés, Coordinate initiation of Drosophila development by regulated polyadenylation of maternal messenger RNAs. 1994, Pubmed
Schnierle, Cap-specific mRNA (nucleoside-O2'-)-methyltransferase and poly(A) polymerase stimulatory activities of vaccinia virus are mediated by a single protein. 1992, Pubmed
Shatkin, Capping of eucaryotic mRNAs. 1976, Pubmed
Sheets, Polyadenylation of c-mos mRNA as a control point in Xenopus meiotic maturation. 1995, Pubmed , Xenbase
Sheets, The 3'-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation. 1994, Pubmed , Xenbase
Shimotohno, Importance of 5'-terminal blocking structure to stabilize mRNA in eukaryotic protein synthesis. 1977, Pubmed
Showman, Translation of maternal histone mRNAs in sea urchin embryos: a test of control by 5' cap methylation. 1987, Pubmed
Simon, Translational control by poly(A) elongation during Xenopus development: differential repression and enhancement by a novel cytoplasmic polyadenylation element. 1992, Pubmed , Xenbase
Simon, Further analysis of cytoplasmic polyadenylation in Xenopus embryos and identification of embryonic cytoplasmic polyadenylation element-binding proteins. 1994, Pubmed , Xenbase
Stebbins-Boaz, Multiple sequence elements and a maternal mRNA product control cdk2 RNA polyadenylation and translation during early Xenopus development. 1994, Pubmed , Xenbase
Vassalli, Regulated polyadenylation controls mRNA translation during meiotic maturation of mouse oocytes. 1989, Pubmed
Wasserman, Protein synthesis during maturation promoting factor- and progesterone-induced maturation in Xenopus oocytes. 1982, Pubmed , Xenbase
Wickens, In the beginning is the end: regulation of poly(A) addition and removal during early development. 1990, Pubmed
Wightman, Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. 1993, Pubmed
Wilt, Polyadenylation of maternal RNA of sea urchin eggs after fertilization. 1973, Pubmed
Winkler, Multiple levels of regulation of protein synthesis at fertilization in sea urchin eggs. 1985, Pubmed
Wormington, Poly(A) and translation: development control. 1993, Pubmed , Xenbase
Yang, Nuclear processing of the 3'-terminal nucleotides of pre-U1 RNA in Xenopus laevis oocytes. 1992, Pubmed , Xenbase
Zelus, Expression of the poly(A)-binding protein during development of Xenopus laevis. 1989, Pubmed , Xenbase