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XB-ART-38334
Dev Cell 2008 Aug 01;152:176-7. doi: 10.1016/j.devcel.2008.07.012.
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Intriguing extracellular regulation of BMP signaling.

Bier E .


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Extracellular components of the BMP signaling pathway bind specific partners with high affinity, implying regulation by dedicated protein-protein interactions. In this and other recent issues of Developmental Cell, new results by Ambrosio et al. (and others) suggest, however, that these factors interact in more complex ways to regulate BMP signaling on a fine scale.

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Species referenced: Xenopus
Genes referenced: tbx2

References [+] :
Ambrosio, Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning. 2008, Pubmed, Xenbase