Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-12546
Semin Cell Dev Biol 1999 Jun 01;103:311-7. doi: 10.1006/scdb.1999.0307.
Show Gene links Show Anatomy links

Activin as a morphogen in Xenopus mesoderm induction.

McDowell N , Gurdon JB .


???displayArticle.abstract???
Activin, a member of the Transforming Growth Factor beta (TGF-beta) superfamily, can behave as a morphogen in cells of the early Xenopus embryo by inducing a range of mesodermal genes in a concentration-dependent manner. This review examines the behaviour of activin as it forms a morphogen gradient. It also discusses how a cell can perceive its position in a concentration gradient in order to activate appropriate mesodermal gene responses.

???displayArticle.pubmedLink??? 10441545
???displayArticle.link??? Semin Cell Dev Biol
???displayArticle.grants??? [+]

Species referenced: Xenopus
Genes referenced: tgfb1