Ciba Found Symp 1989 Jan 01;144:99-109; discussion 109-12, 150-5. doi: 10.1002/9780470513798.ch6.

The establishment of regional identity in the Xenopus blastula.

???displayArticle.abstract???
The molecules involved in the commitment of Xenopus cells to particular germ layers are unknown. The question has been investigated for the cells of the blastula in in vivo cell transplantation assays and in vitro aggregation assays. Using the former technique, we have shown that vegetal cells become committed before gastrulation, even when placed in inappropriate sites. We could find no evidence of regional determination within the endoderm germ layer at the early gastrula stage. In aggregation assays, animal and vegetal cells sorted incompletely at the mid-blastula stage and more efficiently at the gastrula stage. Their behaviour may be mediated by differential expression of adhesion molecules, which so far remain unidentified.

???displayArticle.pubmedLink??? 2776519
???displayArticle.link??? Ciba Found Symp
???displayArticle.grants??? [+]