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XB-ART-25835
Mol Cell Biol 1990 Jun 01;106:2793-800. doi: 10.1128/mcb.10.6.2793-2800.1990.
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A DNA-binding protein is required for termination of transcription by RNA polymerase I in Xenopus laevis.

McStay B , Reeder RH .


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We describe a partially fractionated in vitro transcription system from Xenopus laevis for the assay of transcription termination by RNA polymerase I. Termination in vitro was found to require a specific terminator sequence in the DNA and a DNA-binding protein fraction that produces a footprint over the terminator sequence.

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References [+] :
Bartsch, Purification and characterization of TTFI, a factor that mediates termination of mouse ribosomal DNA transcription. 1988, Pubmed