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EMBO J
1983 Jan 01;212:2271-9. doi: 10.1002/j.1460-2075.1983.tb01734.x.
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Sequence homologies within the 5' end region of the estrogen-controlled vitellogenin gene in Xenopus and chicken.
Walker P
,
Brown-Luedi M
,
Germond JE
,
Wahli W
,
Meijlink FC
,
van het Schip AD
,
Roelink H
,
Gruber M
,
Ab G
.
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In oviparous vertebrates vitellogenin, the precursor of the major yolk proteins, is synthesized in the liver of mature females under the control of estrogen. We have established the organization and primary structure of the 5' end region of the Xenopus laevis vitellogenin A2 gene and of the major chicken vitellogenin gene. The first three homologous exons have exactly the same length in both species, namely 53, 21 and 152 nucleotides, and present an overall sequence homology of 60%. In both species, the 5'-non-coding region of the vitellogenin mRNA measures only 13 nucleotides, nine of which are conserved. In contrast, the corresponding introns of the Xenopus and the chicken vitellogenin gene show no significant sequence homology. Within the 500 nucleotides preceding the 5' end of the genes, at least six blocks with sequence homologies of greater than 70% were detected. It remains to be demonstrated which of these conserved sequences, if any, are involved in the hormone-regulated expression of the vitellogenin genes.
Ab,
Estradiol-induced synthesis of vitellogenin. III. The isolation and characterization of vitellogenin messenger RNA from avian liver.
1976, Pubmed
Ab,
Estradiol-induced synthesis of vitellogenin. III. The isolation and characterization of vitellogenin messenger RNA from avian liver.
1976,
Pubmed
Arnberg,
Isolation and characterization of genomic clones covering the chicken vitellogenin gene.
1981,
Pubmed
,
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Auffray,
Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA.
1980,
Pubmed
Benoist,
In vivo sequence requirements of the SV40 early promotor region.
1981,
Pubmed
Berk,
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.
1977,
Pubmed
Brock,
Estrogen regulates the absolute rate of transcription of the Xenopus laevis vitellogenin genes.
1983,
Pubmed
,
Xenbase
Buetti,
Cloned mouse mammary tumor virus DNA is biologically active in transfected mouse cells and its expression is stimulated by glucocorticoid hormones.
1981,
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Dierks,
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1981,
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Dierks,
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1983,
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Doehmer,
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1982,
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Fromm,
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1982,
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Gerber-Huber,
Estrogen induces tissue specific changes in the chromatin conformation of the vitellogenin genes in Xenopus.
1981,
Pubmed
,
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Germond,
Vitellogenin B2 gene in Xenopus laevis: isolation, in vitro transcription and relation to other vitellogenin genes.
1983,
Pubmed
,
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Grosschedl,
Spacer DNA sequences upstream of the T-A-T-A-A-A-T-A sequence are essential for promotion of H2A histone gene transcription in vivo.
1980,
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,
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Grosveld,
Sequence requirements for the transcription of the rabbit beta-globin gene in vivo: the -80 region.
1982,
Pubmed
Hagenbüchle,
Conservation of the primary structure at the 3' end of 18S rRNA from eucaryotic cells.
1978,
Pubmed
Hamlyn,
Complete sequence of constant and 3' noncoding regions of an immunoglobulin mRNA using the dideoxynucleotide method of RNA sequencing.
1978,
Pubmed
Hynes,
Hormone-responsive expression of an endogenous proviral gene of mouse mammary tumor virus after molecular cloning and gene transfer into cultured cells.
1981,
Pubmed
Konkel,
The sequence of the chromosomal mouse beta-globin major gene: homologies in capping, splicing and poly(A) sites.
1978,
Pubmed
Kurtz,
Hormonal inducibility of rat alpha 2u globulin genes in transfected mouse cells.
1981,
Pubmed
Lomedico,
The structure and evolution of the two nonallelic rat preproinsulin genes.
1979,
Pubmed
Maniatis,
Nucleotide sequence of the rightward operator of phage lambda.
1975,
Pubmed
Manley,
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.
1980,
Pubmed
Maxam,
Sequencing end-labeled DNA with base-specific chemical cleavages.
1980,
Pubmed
McKnight,
Functional relationships between transcriptional control signals of the thymidine kinase gene of herpes simplex virus.
1982,
Pubmed
McKnight,
Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: identification of an upstream control region.
1981,
Pubmed
,
Xenbase
McKnight,
Transcriptional control signals of a eukaryotic protein-coding gene.
1982,
Pubmed
Mellon,
Identification of DNA sequences required for transcription of the human alpha 1-globin gene in a new SV40 host-vector system.
1981,
Pubmed
Messing,
A system for shotgun DNA sequencing.
1981,
Pubmed
Moss,
The putative promoter of a Xenopus laevis ribosomal gene is reduplicated.
1979,
Pubmed
,
Xenbase
Mount,
A catalogue of splice junction sequences.
1982,
Pubmed
Page,
Androgen-regulated expression of a cloned rat prostatic c3 gene transfected into mouse mammary tumor cells.
1983,
Pubmed
Pelham,
A regulatory upstream promoter element in the Drosophila hsp 70 heat-shock gene.
1982,
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Renkawitz,
Expression of a chicken lysozyme recombinant gene is regulated by progesterone and dexamethasone after microinjection into oviduct cells.
1982,
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Robins,
Regulated expression of human growth hormone genes in mouse cells.
1982,
Pubmed
Ryffel,
Quantitation of vitellogenin messenger RNA in the liver of male Xenopus toads during primary and secondary stimulation by estrogen.
1977,
Pubmed
,
Xenbase
Sanger,
DNA sequencing with chain-terminating inhibitors.
1977,
Pubmed
Sassone-Corsi,
Promotion of specific in vitro transcription by excised "TATA" box sequences inserted in a foreign nucleotide environment.
1981,
Pubmed
Sollner-Webb,
The nucleotide sequence of the initiation and termination sites for ribosomal RNA transcription in X. laevis.
1979,
Pubmed
,
Xenbase
Staden,
An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences.
1982,
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Struhl,
Deletion mapping a eukaryotic promoter.
1981,
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Vogt,
Purification and properties of S1 nuclease from Aspergillus.
1980,
Pubmed
Wahli,
Isolation of two closely related vitellogenin genes, including their flanking regions, from a Xenopus laevis gene library.
1980,
Pubmed
,
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Wahli,
Vitellogenin in Xenopus laevis is encoded in a small family of genes.
1979,
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,
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Wahli,
Vitellogenesis and the vitellogenin gene family.
1981,
Pubmed
,
Xenbase
Wahli,
Size, complexity and abundance of a specific poly(A)-containing RNA of liver from male Xenopus induced to vitellogenin synthesis by estrogen.
1976,
Pubmed
,
Xenbase
Wahli,
Comparative analysis of the structural organization of two closely related vitellogenin genes in X. laevis.
1980,
Pubmed
,
Xenbase
Wahli,
Vitellogenin genes A1 and B1 are linked in the Xenopus laevis genome.
1982,
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,
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Wang,
Identificiation, purification, and characterization of two distinct avian vitellogenins.
1980,
Pubmed
Weaver,
Mapping of RNA by a modification of the Berk-Sharp procedure: the 5' termini of 15 S beta-globin mRNA precursor and mature 10 s beta-globin mRNA have identical map coordinates.
1979,
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Wiley,
The structure of vitellogenin. Multiple vitellogenins in Xenopus laevis give rise to multiple forms of the yolk proteins.
1981,
Pubmed
,
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Wilks,
Isolation and fine structure organisation of an avian vitellogenin gene coding for the major estrogen-inducible mRNA.
1981,
Pubmed
,
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Wiskocil,
Coordinate regulation of two estrogen-dependent genes in avian liver.
1980,
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