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Mech Dev 2002 Sep 01;1171-2:163-72. doi: 10.1016/s0925-4773(02)00199-5.
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Defining pallial and subpallial divisions in the developing Xenopus forebrain.

Bachy I , Berthon J , Rétaux S .

To shed light on the organisation of the Xenopus laevis telencephalon, we have used two sets of developmental regulators: genes acting in early regional specification (x-Dll3, x-Nkx2.1, x-Emx1, x-Pax6, x-Eomes) or in cell determination (x-Lhx5 and x-Lhx7). After expression patterns analysis, separately or combined, on whole-mount brains and serial sections, we identify the Xenopus pallium and subpallium, and the subdivisions herein. The data show a conservation of the same basic Bauplan for Xenopus forebrain patterning compared to other vertebrates, and suggest the possibility for LIM-homeodomain genes to be candidate downstream target of the regionalization genes. Comparing the relative sizes of the deduced subdivisions, Xenopus seems to have an intermediate phylogenetic position in terms of pallium contribution to the telencephalon, and ventral pallium contribution to the pallium.

PubMed ID: 12204256
Article link: Mech Dev

Species referenced: Xenopus laevis
Genes referenced: dlc dlx2 dlx5 emx1 eomes hopx lhx5 lhx8 nkx2-1 pax6 tec

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