Title: Coordinated genomic control of ciliogenesis and cell movement by Rfx2
GEO Series: GSE50593
We have performed a systems-level analysis of the RFX/Daf-19 family transcription factor, Rfx2. Using a combination of high-throughput sequencing of Rfx2-regulated transcripts and chromosomal binding sites, we provide a comprehensive accounting of the target genes by which Rfx2 controls ciliogenesis and cilia beating in vertebrates.
Contributors: Taejoon Kwon, Mei-I Chung, Rakhi Gupta, Julie Baker, Edward Marcotte, John Wallingford
Experiment Type: RNA-seq: two biological replicates for control and RFX2 knockdown by morpholino injection, ChIP-seq: RFX2-GFP pulldown with GFP antibody, GFP only expression used as control
Experiment Reagents: rfx2 MO1, Tg(GFP-rfx2).
Article: XB-ART-51735, PubMed
Source: NCBI GEO, Xenbase Download
Samples: (DEG = Differentially Expressed Genes; GSM = GEO Sample Number)
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