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Search Criteria

Gene/Clone	Species	Stage	Anatomy Item	Experimenter
pax6	xenopus		pre-chordal neural plate [+] anterior neural fold,optic field,pre-chordal neural plate border,anterior neural tube,choroid fissure,eye,eye primordium,forebrain,iris,midbrain,optic nerve,optic stalk,optic tectum,optic vesicle,ventral septum,diencephalon,dorsal telencephalon,posterior commissure,anterior commissure,ventral pallidum,nucleus of the diagonal band,bipolar neuron,optic stalk,mesencephalic artery,anterior amygdala,optic chiasm,posteroventral tegmental nucleus,retinal stem cell,pallidum,anteroventral tegmental nucleus,peripheral retina,caudal tuberal region,anterior thalamic nucleus,olfactory bulb,cornea,ventral pallium,pupil,granule cell,thalamus,choroid,dorsal tegmentum,sclera,horizontal cell,ventral hypothalamic nucleus,mitral cell,retinal inner plexiform layer,optic fiber layer,suprachiasmatic nucleus,ciliary marginal zone,central retina,medial ganglionic eminence,retinal stem cell region,lateral septum,lateral amygdala,lens transitional zone,mesencephalic vein,preoptic area,pigment layer,dorsal pallium,inner limiting membrane,retinal outer nuclear layer,hypothalamus,choroid fissure,retinal ganglion cell,midbrain tegmentum,magnocellular preoptic nucleus,subcommissural organ,retinal pigmented epithelium,ventromedial thalamic nucleus,retromammillary area,nucleus accumbens,pineal gland,prethalamus,accessory olfactory bulb,pallium,external plexiform layer of the olfactory bulb,retinal inner nuclear layer,optic tract,eminentia thalami,anterior entopeduncular region,posterior tectum,conjunctiva,rostral tuberal region,prethalamus basal plate,habenula,amacrine cell,telencephalon septum,infundibulum,outer segment cilium,granule cell layer of the olfactory bulb,neurohypophysis,eye photoreceptor cell,optic tectum,adenohypophysis,retinal layer,ventricular layer of the optic tectum,glial endfoot,radial glial cell,laterodorsal tegmental nucleus,lateral forebrain bundle,medial pallium,dorsal habenular nucleus,ventral habenular nucleus,retinal ganglion cell layer,retinal neural layer,melanotrope,pars intermedia,retinal progenitor cell region,anterodorsal tegmental nucleus,prosomere,lens fiber cell mass,supraoptoparaventricular region,torus semicircularis,cell body layer of the optic tectum,oculomotor motornucleus,ciliary body,iris,telencephalon,striatum,lateral pallium,pretectum,optic nerve,subthalamic nucleus,retina,lateral hypothalamic nucleus,dorsal pallidum,ventrolateral thalamic nucleus,central nucleus of the thalamus,bed nucleus of the stria terminalis,dorsal septum,pars nervosa,tuberal region,anterior entopeduncular nucleus,zona limitans intrathalamica,lens epithelium,pars distalis,medial septum,mammilary region,third ventricle,medial amygdala,prosomere 4,central amygdala,retinal outer plexiform layer,subpallium,posterodorsal tegmental nucleus,trochlear motornucleus,neuropil of the optic tectum,mitral cell layer of the olfactory bulb,anterior hypothalamus,hypophysis,basal forebrain,lens placode,dorsal thalamus,Mueller cell,ventral tegmentum,globe,prosomere 6,optic disc,lateral ganglionic eminence,prosomere 5,retinal progenitor cell,lens,amygdala,outer segment disk,posterior hypothalamus,outer limiting membrane,lower eyelid,glomerular layer of the olfactory bulb,photoreceptor layer,anterior tectum,basal ganglion

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Expression summary for pax6

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Experiment	Species	Images	Stages	Anatomy	Assay
Wu J et al. (2006) Assay Paper	laevis	2 images	NF stage 14 to NF stage 20	anterior neural tube, eye primordium, pre-chordal neural plate	in situ hybridization
Zaghloul NA and Moody SA (2007) Assay Paper	laevis	1 image	NF stage 20 to NF stage 37 and 38	ciliary marginal zone, diencephalon, eye, eye primordium, lens, [+] lens placode, optic vesicle, retina, retinal ganglion cell layer, retinal inner nuclear layer	in situ hybridization
Atkinson-Leadbeater K et al. (2009) Assay Paper	laevis	2 images	NF stage 21 to NF stage 25	diencephalon, optic vesicle, retina, telencephalon	in situ hybridization
Schlosser G and Ahrens K (2004) Assay Paper	laevis	7 images	NF stage 13 to NF stage 33 and 34	diencephalon, lens, lens placode, midbrain, optic vesicle, [+] pre-chordal neural plate	in situ hybridization
Offner N et al. (2005) Assay Paper	laevis	1 image	NF stage 18	pre-chordal neural plate	in situ hybridization
Zuber ME et al. (2003) Assay Paper	laevis	1 image	NF stage 12.5	pre-chordal neural plate	in situ hybridization
Dichmann DS et al. (2008) Assay Paper	laevis	2 images	NF stage 17 to NF stage 31	anterior neural fold, diencephalon, eye, eye primordium, forebrain, [+] lens placode, midbrain, pre-chordal neural plate, retina	in situ hybridization
Mamada H et al. (2009) Assay Paper	laevis	2 images	NF stage 13 to NF stage 14	eye primordium	in situ hybridization
Murato Y and Hashimoto C (2009) Assay Paper	laevis	1 image	NF stage 16	anterior neural fold, lens placode	in situ hybridization
Rodríguez-Seguel E et al. (2009) Assay Paper	laevis	2 images	NF stage 14 to NF stage 16	anterior neural fold, diencephalon, pre-chordal neural plate	in situ hybridization
Harland Lab Assay Harland Lab	tropicalis	4 images	NF stage 13 to NF stage 33 and 34	diencephalon, eye, eye primordium, lens, pre-chordal neural plate, [+] retina, telencephalon	in situ hybridization
Paper	laevis	2 images	NF stage 21 to NF stage 35 and 36	eye, optic field	in situ hybridization
Neural crest migration requires the activity of the extracellular sulphatases XtSulf1 and XtSulf2. Paper	tropicalis	1 image	NF stage 28	anterior neural tube, eye, forebrain, midbrain	in situ hybridization
FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development. Paper	laevis	1 image	NF stage 13 to NF stage 23	anterior neural fold, eye primordium	in situ hybridization
FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development. Paper	laevis	1 image	NF stage 13 to NF stage 23	anterior neural fold, eye primordium	in situ hybridization
FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development. Paper	laevis	1 image	NF stage 13 to NF stage 23	eye primordium, optic field	in situ hybridization
FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development. Paper	laevis	1 image	NF stage 13 to NF stage 23	eye primordium, optic field	in situ hybridization
FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development. Paper	laevis	1 image	NF stage 13 to NF stage 23	optic field	in situ hybridization
FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development. Paper	laevis	1 image	NF stage 13 to NF stage 23	eye primordium, optic field	in situ hybridization
Role of X-Delta-2 in the early neural development of Xenopus laevis. Paper	laevis	1 image	NF stage 21 to NF stage 25	anterior neural tube, forebrain, optic vesicle	in situ hybridization
Effects of retinoic acid upon eye field morphogenesis and differentiation. Paper	laevis	1 image	NF stage 12.5	anterior neural fold	in situ hybridization
Autoregulation of canonical Wnt signaling controls midbrain development. Paper	laevis	2 images	NF stage 29 and 30	eye, midbrain	in situ hybridization
Highly efficient transgenesis in Xenopus tropicalis using I-SceI meganuclease. Paper	tropicalis	1 image	NF stage 26	eye	in situ hybridization
Defining pallial and subpallial divisions in the developing Xenopus forebrain. Paper	laevis	4 images	NF stage 32 to NF stage 40	diencephalon, dorsal pallium, eye, forebrain, lateral ganglionic eminence, [+] lateral pallium, lens, medial pallium, pallium, pineal gland, pretectum, prethalamus, prosomere, prosomere 4, retina, telencephalon, ventral pallium, zona limitans intrathalamica	in situ hybridization
Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase. Paper	laevis	1 image	NF stage 13 to NF stage 35 and 36	eye, forebrain, pre-chordal neural plate	in situ hybridization
Morphogenetic movements underlying eye field formation require interactions between the FGF and ephrinB1 signaling pathways. Paper	laevis	1 image	NF stage 16	optic field	in situ hybridization
A novel function for Hedgehog signalling in retinal pigment epithelium differentiation. Paper	laevis	1 image	NF stage 39	eye, retina, retinal neural layer	in situ hybridization
The homeodomain factor Xanf represses expression of genes in the presumptive rostral forebrain that specify more caudal brain... Paper	laevis	1 image	NF stage 28	diencephalon, eye	in situ hybridization
Alterations of rx1 and pax6 expression levels at neural plate stages differentially affect the production of retinal cell typ... Paper	laevis	1 image	NF stage 20	eye primordium, lens placode, optic vesicle, retina	in situ hybridization
Alterations of rx1 and pax6 expression levels at neural plate stages differentially affect the production of retinal cell typ... Paper	laevis	1 image	NF stage 20	diencephalon, eye primordium, optic vesicle, retina	in situ hybridization
A novel function for Hedgehog signalling in retinal pigment epithelium differentiation. Paper	laevis	1 image	NF stage 39	eye, retina, retinal neural layer	in situ hybridization
Olfactory and lens placode formation is controlled by the hedgehog-interacting protein (Xhip) in Xenopus. Paper	laevis	1 image	NF stage 14	anterior neural fold, eye primordium	in situ hybridization
Roles of ADAM13-regulated Wnt activity in early Xenopus eye development. Paper	laevis	2 images	NF stage 12.5	pre-chordal neural plate	in situ hybridization
Argasinska J et al. (2009) Assay Paper	laevis	1 image	NF stage 28	eye, midbrain	in situ hybridization
Elkins MB and Henry JJ (2006) Assay Paper	laevis	1 image	NF stage 35 and 36	lens, lens fiber cell mass, retina, retinal neural layer	in situ hybridization
Transgenic Xenopus embryos reveal that anterior neural development requires continued suppression of BMP signaling after gast... Paper	laevis	5 images	NF stage 14 to NF stage 32	anterior neural fold, diencephalon, eye, eye primordium, lens placode, [+] midbrain, optic vesicle, pre-chordal neural plate, retina	in situ hybridization
Differential distribution of competence for panplacodal and neural crest induction to non-neural and neural ectoderm. Paper	laevis	1 image	NF stage 22	anterior neural fold, lens epithelium	in situ hybridization
Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis. Paper	laevis	1 image	NF stage 22	eye, optic field, optic vesicle, retina	in situ hybridization
Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis. Paper	laevis	1 image	NF stage 29 and 30	eye, lens placode, retina	in situ hybridization
Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development. Paper	laevis	1 image	NF stage 14	anterior neural fold, optic field, pre-chordal neural plate	in situ hybridization
Xu Y et al. (2012) Assay Paper	laevis	1 image	NF stage 19	eye primordium	in situ hybridization
Regulation of eye development by frizzled signaling in Xenopus.	laevis	1 image	NF stage 45	eye, lens, retina	immunohistochemistry
Regulation of eye development by frizzled signaling in Xenopus. Paper	laevis	1 image	NF stage 14 to NF stage 28	eye	in situ hybridization
Regulation of eye development by frizzled signaling in Xenopus. Paper	laevis	1 image	NF stage 18 to NF stage 20	eye primordium, optic field	in situ hybridization
Perron M et al. (1998) Assay Paper	laevis	2 images	NF stage 40	ciliary marginal zone, eye, retina, retinal ganglion cell layer, retinal inner nuclear layer	in situ hybridization
Microarray-based identification of Pitx3 targets during Xenopus embryogenesis. Paper	laevis	1 image	NF stage 19 to NF stage 27	eye, eye primordium, forebrain, telencephalon	in situ hybridization
A homolog of Subtilisin-like Proprotein Convertase 7 is essential to anterior neural development in Xenopus. Paper	laevis	1 image	NF stage 28	retina	in situ hybridization
Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning. Paper	laevis	1 image	NF stage 17	lens, optic field	in situ hybridization
Roles of ADAM13-regulated Wnt activity in early Xenopus eye development. Paper	laevis	1 image	NF stage 12.5	optic field	in situ hybridization
Roles of ADAM13-regulated Wnt activity in early Xenopus eye development. Paper	laevis	1 image	NF stage 12.5	pre-chordal neural plate	in situ hybridization

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