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Gene/Clone	Species	Stage	Anatomy Item	Experimenter
actc1	xenopus		otic vesicle [+] amphibian papilla,anterior crista,auditory hair cell,auditory ossicle,auditory tube,basilar papilla,endolymphatic duct,footplate of the stapes,inner ear,lagena,lateral crista,middle ear,osseous labyrinth,otic capsule,oval window,pars externa of the stapes,pars interna of the stapes,pars media of the stapes,posterior crista,prootic bone,saccular macula,semicircular canal,stapes,tympanic annulus,tympanic disk,vestibular apparatus,vestibule,auditory apparatus,otic capsule

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Experiment details for actc1

Lymph heart musculature is under distinct developmental control from lymphatic endothelium.

Gene	Clone	Species	Stages	Anatomy
actc1.L		laevis	NF stage 40	otic vesicle

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Fig. 1. Lymph heart myoblasts express skeletal muscle markers and not cardiac markers. The 12/101 antibody marks lymph hearts in stage 42 tadpoles (A, C, and M) and MyoD is expressed in differentiating lymph hearts at stage 40 (B, arrows). Two bilaterally symmetrical lymph hearts can be seen adjacent to the somites (A, B, arrows). The lymph heart forms in a region adjacent to somites 3 and 4 (C, K, trunk somites are numbered). Lymph heart muscle consists of a meshwork of myotubes (C). The lymph heart does not express cardiac markers GATA4 (D, E), cardiac troponin (F, G), or cardiac actin (H, I) at st. 33/34 (D, F, and H) or st. 40 (E, G, and I), except for cardiac actin at st. 40 (I, arrow), which marks all immature muscle (note expression in paraxial and head mesoderm in H, I). Rhodamine-dextran (mini-Ruby) injected subcutaneously into the posterior ventral tail fin drains anteriorly into the kidney (J, bright spot with asterisk) and into the lymph heart through vessels (J, arrowhead). The labeled lymph heart is located between somites 3 and 4 (K). Embryos injected with rhodamine-dextran (L, red) and then stained for the skeletal muscle antibody 12/101 (M, green) show co-expression (M', yellow). All lateral views, anterior left, except for (A, B), which are dorsal views.