| |
Additional Figure 2. Temporal and spatial expression pattern of alk3 and alk6. (A) Expression pattern
in tadpole stage embryos. Alk3 mRNA is detected in the brain, the eye, predominantly in the lens (A, A‘),
the otic vesicle (A, A‘‘), branchial arches, pronehphros, intersomitic tissue and dorsal fin mesenchyme (A,
A‘‘‘). Alk6 is expressed in a more restricted pattern. Transcripts were detected in two narrow stripes in the
brain, the ventral part of the eye, otic vesicle, branchial archs and the notochord (B, B‘‘‘). Expression was
further limited to the dorsal part of the neural tube, the ventral retina (B‘), and a dorso-lateral patch of the
otic vesicle (B‘‘). Hybridization with sense probes yielded no specific staining in any embryonic stage analyzed
(C). |
