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Gene/CloneSpeciesStageAnatomy ItemExperimenter
irx1xenopus hindlimb bud [+] 

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Experiment details for irx1

Evidence for an amphibian sixth digit.

Evidence for an amphibian sixth digit.

Gene Clone Species Stages Anatomy
irx1 tropicalis NF stage 53 hindlimb bud , hindlimb digit 4

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  Figure S3. irx1 expression specific for digit condensation of the X. tropicalis hindlimb bud. A, sox9 expression at stage 53. Precartilaginous condensation, including the first visible condensation of digit IV, was detectable. B, irx1 expression at stage 53. irx1 was exclusively expressed in the digit condensation of digit IV at this stage, and other cartilaginous regions were irx1-negative, indicating that irx1 expression is specific for developing digits. Scale bar: 200 μm.

Gene Clone Species Stages Anatomy
irx1 tropicalis NF stage 55 hindlimb

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  Fig. 5 Molecular marker expression in the developing hindlimb of X. tropicalis. a-f, Gene expression detected by section in situ hybridization. a, b, Expression of shh at stages 51 (a) and 52 (b). c, Expression of sox9 at stage 55. e, Expression of irx1 at stage 55. Cartilaginous condensation for the anlage of the protrusion (bracket) was irx1-posititve. d, f, High-magnification images of those in (c) and (e). Note that irx1 was highly expressed in the anlage of the protrusion (bracket in f). Cartilaginous primordium of the protrusion is indicated by the bracket. Scale bars: 200 μm