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Figure 2. Spatial expression pattern of ProSAP1/Shank2 during Xenopus embryogenesis. A: Lateral view of an embryo at stage 23. ProSAP1/Shank2 is expressed in the otic vesicle (white arrowhead). B: Lateral view of an embryo at stage 25. ProSAP1/Shank2 transcripts are detected in the otic vesicle (white arrowhead), pronephric anlage (black arrow), forebrain (red arrowhead), isthmus (green arrowhead), and hindbrain (white arrow). C: Anterior view of the embryo shown in C. ProSAP1/Shank2 can be visualized in the forebrain (red arrowheads) and the isthmus (green arrowhead). D–G: Lateral views of Xenopus embryos at stages indicated. ProSAP1/Shank2 expression is demonstrated in the otic vesicle (white arrowhead), developing pronephros (black arrow and arrowhead), forebrain (red arrowhead), isthmus (green arrowhead), and hindbrain (white arrow). In addition, ProSAP1/Shank2 transcription in the liver begins (red arrow). Dotted lines indicate the level of transverse sections shown in H-O. H: ProSAP1/Shank2 is expressed in the proximal and intermediate tubule (arrow). I: ProSAP1/Shank2 transcripts are detected in the connecting tubule anlage (arrowhead). J: ProSAP1/Shank2 expression is clearly seen in the isthmus (green arrowhead). K: The transverse sections through an embryo at stage 36 display ProSAP1/Shank2 expression in the ventral interneurons of the hindbrain (white arrow). L: ProSAP1/Shank2 is expressed in the otic vesicle (white arrowhead) as well as the hindbrain (white arrow) at stage 36. M: ProSAP1/Shank2 transcripts can be visualized in the proximal and intermediate pronephric tubules (black arrow). N: At stage 40, ProSAP1/Shank2 is expressed in the retina of the eye (blue arrowhead). O: The transverse section shows that ProSAP1/Shank2 transcripts are strongly detectable in the liver (red arrow).Download figure to PowerPoint |
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shank2( SH3 and multiple ankyrin repeat domains 2 ) gene expression in Xenopus laevis embryos, NF stage 31, as assayed by in situ hybridization. Lateral view: anterior right, dorsal up.
Copyright Wiley-Liss , 2011
Image published in: Gessert S et al. (2011)
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shank2( SH3 and multiple ankyrin repeat domains 2 ) gene expression in Xenopus laevis embryos, NF stage 33, as assayed by in situ hybridization. Lateral view: anterior right, dorsal up.
Copyright Wiley-Liss , 2011
Image published in: Gessert S et al. (2011)
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shank2( SH3 and multiple ankyrin repeat domains 2 ) gene expression in Xenopus laevis embryos, NF stage 36, as assayed by in situ hybridization. Lateral view: anterior right, dorsal up.
Copyright Wiley-Liss , 2011
Image published in: Gessert S et al. (2011)
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