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FIG. 2. Whole-m ount in situ hybridization analysis of Pax-3 expression in Xenopus em bryos. (A) Dorsovegetal view at stage 11.5 showing that Pax-3 is expressed in distinct lateral domains of the presumptive neural plate. (B) Dorsal view at stage 13 showing the refinement of Pax-3 expression to lateral dom ains of the neural plate during convergence and extension. (C) Dorsovegetal view at stage 11.5 showing that XWnt-8 is expressed in involuting ventral-lateral mesoderm. ingsof involuted mesoderm that underlie the prospective lateral neural plate are indicated by arrows. (D) Dorsal view at stage 13 showing XWnt-8 expression in the lateral neural plate. |