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Experiment details for tlx1

Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of Six1 and Eya1 in cranial placodes.

Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of Six1 and Eya1 in cranial placodes.

Gene Clone Species Stages Anatomy
tlx1.L laevis NF stage 28 otic vesicle , trigeminal placode , primary heart field , secondary heart field , lateral line ganglion , [+]

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  Figure 7. Up-regulation of target gene expression domains after overexpression of Eya1. Tail bud stage embryos (A–G) after unilateral injection of Eya1-GR and DEX induction at neural plate stage (16–18). In each case, lacZ was co-injected as a lineage tracer and panels A1–G1 show the control (un-injected) side and A2–G2 show the injected side. Arrows and arrowheads mark expansions in marker gene expression in placodal and non-placodal derivatives, respectively.