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tlx1xenopus   

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Experiment details for tlx1

Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of Six1 and Eya1 in cranial placodes.

Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of Six1 and Eya1 in cranial placodes.

Gene Clone Species Stages Anatomy
tlx1.L laevis NF stage 24 otic placode , profundus ganglion , lateral line placode , profundal placode , ventral mesoderm

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  Figure 5—figure supplement 1. Effects of Six1 knockdown on target genes. Tail bud stage (A–G) and neural plate stage (H–J) embryos after unilateral injection of Six1-MO1+2. In each case, lacZ was co-injected as a lineage tracer and panels A1–G1 show the control (un-injected) side and A2–G2 show the injected side. The injected side is positioned to the right in H–J, as marked by blue lacZ staining (lacZ staining out of frame in some specimens). Arrows mark reductions in marker gene expression in placodal derivatives, and asterisks indicate increased expression.