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FIG. 1. Early expression of XAP-2. Whole mount in situ hybridizations
at stage 10.25 (A) and stage 12.5–13 (B) to antisense XAP-2
probe, stained with BM-purple. In panel A, the arrowhead indicates
hybridization to a chordin probe to mark the dorsal lip (magentaphos
stain). At the beginning of gastrulation, XAP-2 RNA was
found throughout the ectoderm, then becomes excluded from the
neural plate by the end of gastrulation, at which time high level
expression commences in the cranial neural crest region. |