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Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
foxc1
|
|
laevis
|
NF stage 10
|
mesoderm
,
ventro-lateral marginal zone
,
involuting marginal zone
,
involuted ventral mesoderm
,
vegetal part, early involuting
|
foxc1
|
|
laevis
|
NF stage 18
|
mesoderm
,
lateral plate mesoderm
,
presumptive paraxial mesoderm
|
foxc1
|
|
laevis
|
NF stage 28
|
head mesoderm
,
prechordal plate
,
tail region
,
chordoneural hinge
,
pronephric mesenchyme
,
[+]
|
hes5.3
|
|
laevis
|
NF stage 11
|
mesoderm
,
involuting marginal zone
,
vegetal part, early involuting
|
hes5.3
|
|
laevis
|
NF stage 18
|
mesoderm
,
presomitic mesoderm
,
tail region
|
hes5.3
|
|
laevis
|
NF stage 28
|
retina
,
brain
,
forebrain
,
midbrain
,
hindbrain
,
[+]
|
hes5.1
|
|
laevis
|
NF stage 11
|
chordal neural plate
,
mesoderm
,
lateral plate mesoderm
|
hes5.1
|
|
laevis
|
NF stage 18
|
chordal neural plate
,
mesoderm
,
presomitic mesoderm
,
trigeminal placode
,
Rohon-Beard neuron
|
hes5.1
|
|
laevis
|
NF stage 28
|
otic vesicle
,
retina
,
brain
,
forebrain
,
midbrain
,
[+]
|
myf5
|
|
laevis
|
NF stage 11
|
dorso-lateral marginal zone
,
involuting marginal zone
|
myf5
|
|
laevis
|
NF stage 18
|
presomitic mesoderm
,
presumptive paraxial mesoderm
|
myf5
|
|
laevis
|
NF stage 28
|
spinal cord
,
presomitic mesoderm
,
somite
,
tail region
,
chordoneural hinge
|
rbm24
|
|
laevis
|
NF stage 10
|
ventral marginal zone
,
ventro-lateral marginal zone
,
dorso-lateral marginal zone
,
involuting marginal zone
|
rbm24
|
|
laevis
|
NF stage 18
|
presomitic mesoderm
,
paraxial mesoderm
|
rbm24
|
|
laevis
|
NF stage 28
|
presomitic mesoderm
,
paraxial mesoderm
,
intersomitic region
|
msgn1
|
|
laevis
|
NF stage 10
|
mesoderm
,
ventro-lateral marginal zone
,
involuting marginal zone
,
involuted ventral mesoderm
|
msgn1
|
|
laevis
|
NF stage 18
|
mesoderm
,
presomitic mesoderm
,
paraxial mesoderm
|
msgn1
|
|
laevis
|
NF stage 28
|
mesoderm
,
tail region
,
tail bud
,
chordoneural hinge
|
myod1
|
|
laevis
|
NF stage 11
|
mesoderm
,
ventral marginal zone
,
ventro-lateral marginal zone
,
dorso-lateral marginal zone
,
involuting marginal zone
|
myod1
|
|
laevis
|
NF stage 18
|
presomitic mesoderm
,
paraxial mesoderm
|
myod1
|
|
laevis
|
NF stage 28
|
presomitic mesoderm
,
somite
,
myotome
|
|
|
Fig. 3. Expression patterns of shortlisted targets. In situ hybridisation analysis of Esr1, Esr2, FoxC1, mesogenin (MSGN1), Myf5, SEB4 and Tbx6 expression patterns at gastrula, neurula and tailbud stages. All the putative target genes are expressed circumblastoporally at gastrula stages. After gastrula stages, many of the targets are still expressed in the posterior mesoderm in the tailbud region of the embryo, which is the source of myogenic progenitors at this stage. On the right, a temporal expression profile, based on microarray data, is shown for each putative target genes depicting relative expression levels from NF stage 8 to stage 15. The expression of MyoD is shown in the three bottom panels for comparison. |