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sox4xenopus   

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Experiment details for sox4

Evolutionarily conserved role for SoxC genes in neural crest specification and neuronal differentiation.

Evolutionarily conserved role for SoxC genes in neural crest specification and neuronal differentiation.

Gene Clone Species Stages Anatomy
sox4.L laevis NF stage 14 pre-chordal neural plate , chordal neural plate , neural plate , anterior neural fold
sox4.L laevis NF stage 17 mandibular crest , hyoid crest , branchial crest , neural plate , cranial neural crest
sox4.L laevis NF stage 20 mandibular crest , hyoid crest , branchial crest , stomodeal-hypophyseal primordium , optic vesicle , [+]
sox4.L laevis NF stage 26 to NF stage 28 otic vesicle , brain , forebrain , midbrain , hindbrain , [+]

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  Fig. 2. Xenopus laevis SoxCs exhibit overlapping expression in the neural plate, neural crest, and facial region. Sox4 (St.14–28) is expressed broadly in the neural plate starting at stage 14/15 and in the forming neural tube and migrating neural crest (Dorsal: A–C). It is then strongly expressed in developing ganglia as well as weakly in the branchial arches, otic vesicle, and eye (D and E). Sox11 (St.14–28) is strongly expressed early in the neural plate border and neural folds (Dorsal:H). It is expressed in neural crest and ectodermal placodes (Dorsal:F–J). Expression is maintained in the neural tube, forming ganglia, and branchial arches (I and J). Sox12 (st.14–28) is expressed broadly and similarly to Sox4. At St 14–20, Sox12 is expressed throughout the neural plate and in the migrating neural crest (Dorsal:K–M). Expression is observed throughout the neural tube as well as in cranial ganglia, branchial arches, eye, and otic vesicle (N and O). Ot: Otic Vesicle; BA: Branchial Arches.