|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
snai1
|
|
laevis
|
NF stage 14
|
neural plate
,
anterior neural fold
,
neural fold
|
gli2
|
|
laevis
|
NF stage 14
|
neuroectoderm
,
neural plate
|
gli1
|
|
laevis
|
NF stage 14
|
neuroectoderm
,
neural groove
,
neural plate
|
zic2
|
|
laevis
|
NF stage 14
|
neural plate
,
lateral
,
anterior neural fold
|
runx1
|
|
laevis
|
NF stage 14
|
neuroectoderm
,
neural plate
,
sensorial layer of neurectoderm
,
lateral
,
neuron
|
gli3
|
|
laevis
|
NF stage 14
|
neuroectoderm
,
neural plate
,
anterior neural fold
|
foxa4
|
|
laevis
|
NF stage 14
|
neural plate
|
snai2
|
|
laevis
|
NF stage 14
|
neural plate
|
shh
|
|
laevis
|
NF stage 14
|
neuroectoderm
,
neural groove
,
neural plate
|
myt1
|
|
laevis
|
NF stage 14
|
neuroectoderm
,
neural groove
,
neural plate
,
lateral
|
ascl2
|
|
laevis
|
NF stage 14
|
neuroectoderm
,
neural plate
,
neural fold
,
presumptive rhombomere
|
|
|
Fig. 2. Effects of Gli3 in neural plate patterning. Whole-mount in situ hybridizations on stage 14 embryos injected (inj.) with MO-C or MO-3 with probes as indicated on the left side of each panel. The β-gal tracer is red except in Pintallavis-MO-3 and the BrdU panels, in which it is blue. Arrows indicate the inhibition of Gli1, Xash3, XMyt1, Xaml, Slug and Snail expressions. Double-headed arrows indicate the size of the neural plate assessed by Sox3 expression. BrdU incorporation in stage 14 embryos injected with MO-3 is shown in brown. A high magnification panel (bottom right) shows BrdU incorporation in the neural plate of a unlilaterally injected MO-3+lacZ embryo. |