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Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
sox2
|
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laevis
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NF stage 18
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pre-chordal neural plate
,
chordal neural plate
,
eye primordium
,
optic vesicle
,
neural groove
,
[+]
|
tlx1
|
|
laevis
|
NF stage 28
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otic vesicle
,
heart
,
trigeminal placode
,
trigeminal ganglion
,
primary heart field
,
[+]
|
isl2
|
|
laevis
|
NF stage 28
|
otic vesicle
,
spinal cord
,
trigeminal placode
,
trigeminal ganglion
,
trigeminal nerve
,
[+]
|
neurog1
|
|
laevis
|
NF stage 18
|
chordal neural plate
,
Rohon-Beard neuron
,
chordal neural plate border
,
neurogenic placode
|
gfi1
|
|
laevis
|
NF stage 28
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ventral blood island
,
trigeminal placode
,
lateral line ganglion
,
neurogenic placode
|
hes5.4
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|
laevis
|
NF stage 28
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olfactory placode
,
retina
,
eye
,
trigeminal placode
,
trigeminal ganglion
,
[+]
|
pou4f4
|
|
laevis
|
NF stage 28
|
otic vesicle
,
trigeminal placode
,
trigeminal ganglion
,
trigeminal nerve
,
neurogenic placode
|
atoh1
|
|
laevis
|
NF stage 28
|
otic vesicle
,
hindbrain
,
neurogenic placode
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hes5.6
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|
laevis
|
NF stage 28
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retina
,
forebrain
,
telencephalon
,
midbrain
,
hindbrain
,
[+]
|
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Figure 5.
Effects of Eya1 knockdown on target genes.
Tail bud (A–G) and neural plate (H–I) stage embryos after unilateral injection of Eya1-MO1+2. In each case, lacZ was co-injected as a lineage tracer and panels A1–G1 show the control (un-injected) side and A2–G2 show the injected side (lacZ staining out of frame in most specimens). The injected side is positioned to the right in H–J, as marked by blue lacZ staining. Arrows and arrowheads mark reductions in marker gene expression in placodal and non-placodal derivatives, respectively.
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