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Fig. 2. Inhibition of ErbB signaling did not interfere with mesodermal induction in early frog embryos. (A) Expression of the mesodermal marker Brachyury (Xbra), the dorsal mesodermal marker Chordin and the head mesodermal marker Goosecoid was not blocked by loss of ErbB signaling in frog gastrulae. (B) At neurula stages, transcription of the notochord markers Xbra and chordin as well as the neural marker Sox3 was not impaired. The pattern of dorsal gene expression was wider and shorter in ErbB-inhibited embryos compared with that in control embryos. |
