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sox3xenopus   

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Experiment details for sox3



BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus.

Gene Clone Species Stages Anatomy
sox3.S laevis NF stage 14 neuroectoderm , neural plate
sox3.S laevis NF stage 15 neuroectoderm , pre-chordal neural plate , chordal neural plate , neural plate
sox3.S laevis NF stage 16 neuroectoderm , pre-chordal neural plate , chordal neural plate , neural plate
sox3.S laevis NF stage 17 pre-chordal neural plate , chordal neural plate , trigeminal placode , neural plate , neural tube
sox3.S laevis NF stage 18 trigeminal placode , neural tube
sox3.S laevis NF stage 20 trigeminal placode , posterior neural tube , anterior neural tube , neural tube

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  Fig. 1. Ventralized embryos express residual sox2 and sox3. X. laevis embryos were injected in both blastomeres at the two cell stage with β-catenin MO, then raised to the stage indicated, fixed in MEMFA, dehydrated and stained by in situ hybridization for expression of sox2 (A) or sox3 (B). Uninjected control sibling embryos are shown at right for each stage. For β-catenin morphants, a ring of sox2 expression is evident around the blastopore between stages 14 and 16, which fades and has disappeared by stage 19. The same pattern is seen for sox3. Embryos are shown in dorsal views with anterior to the top.