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Experiment details for ski

Expression of ski can act as a negative feedback mechanism on retinoic acid signaling.

Expression of Ski can act as a negative feedback mechanism on retinoic acid signaling.

Gene Clone Species Stages Anatomy
ski.S laevis NF stage 11 marginal zone
ski.S laevis NF stage 20 neural plate , ventral , anterior neural tube , anterior neural fold , cranial neural crest , [+]
ski.S laevis NF stage 22 brain , midbrain , anterior neural tube , cranial neural crest , head , [+]
ski.S laevis NF stage 25 olfactory placode , midbrain , mandibular crest , hyoid crest , cranial neural crest , [+]
ski.S laevis NF stage 29 and 30 brain , midbrain , hindbrain , spinal cord , pharyngeal arch , [+]

  Fig. 1. Endogenous expression of ski in Xenopus. Ski expression was first detectable in a ring around the blastopore at stage 10/11. At stage 20, strong expression was observed in bands in the forming head in the anterior (ant.) view There is also staining on the ventral mid- line immediately posterior to the cement gland at that stage. In a dorsal view, strong staining can be seen in the anterior spinal cord (black arrow) and the staining can be seen even fur- ther posterior at stage 22. Strong staining was also observed in the migrating anterior neural crest (red arrowheads). At tail bud stages (St. 30) low levels of expression are seen over much of the embryo including somites and higher expression was still viewed in discrete regions including the otic vesicle (yellow arrow).