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six3xenopus   

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Experiment details for six3

Terada K et al. (2006) Assay

Nucleosome regulator Xhmgb3 is required for cell proliferation of the eye and brain as a downstream target of Xenopus rax/Rx1.

Gene Clone Species Stages Anatomy
six3 xenopus NF stage 17 to NF stage 18 eye primordium , neural plate

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  Fig. 4. Rax is required for the initial expression of XOptx2 mRNA in Xenopus. (A–I) Embryos were injected at 4- or 8-cell stage into one dorsal blastomere on the animal side and injected side is indicated by β-gal activity in blue. Embryos (stages 17/18) injected with rax MO or rax-EnR RNA with β-gal RNA (A–H). Expression of XOptx2 (A, B and F), Pax6 (C, D and G) or Six3 (E, H). Anterior views with dorsal to the top (A–H). (I) Embryos (stages 37/38) injected with rax MO (0.5 pmol). Dorsal views with anterior to the top (I). Yellow arrows indicate reduced eyes (I).

Gene Clone Species Stages Anatomy
six3 xenopus NF stage 17 to NF stage 18 neural plate

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  Fig. 6. Functional activity of Xhmgb3 in the anterior neural plate. An embryo (stage 13) (A), embryos (stages 17/18) (B–L). Embryos were injected with synthetic RNAs and/or Xhmgb3 MO as indicated at the top of each panel (A–L). Expression of rax (A, B, C, F, G and H), Pax6 (D), Six3 (E), XOptx2 (I and J) or XEn2 (K and L). The injected side is indicated by β-gal activity in blue (B–L) or by a yellow arrow (A).