|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
rps14
|
|
tropicalis
|
NF stage 4 (8-cell)
|
animal blastomere
,
blastomere
|
rps14
|
|
tropicalis
|
NF stage 10
|
|
rps14
|
|
tropicalis
|
NF stage 14
to
NF stage 15
|
posterior
|
rps14
|
|
tropicalis
|
NF stage 22
|
cranial neural crest
|
rps14
|
|
tropicalis
|
NF stage 28
to
NF stage 29 and 30
|
brain
,
pharyngeal arch
,
mandibular arch
,
hyoid arch
,
branchial arch
,
[+]
|
rps14
|
|
tropicalis
|
NF stage 35 and 36
to
NF stage 40
|
head
|
rps29
|
|
tropicalis
|
NF stage 3 (4-cell)
|
|
rps29
|
|
tropicalis
|
NF stage 10
|
|
rps29
|
|
tropicalis
|
NF stage 14
to
NF stage 15
|
neural plate
|
rps29
|
|
tropicalis
|
NF stage 22
|
optic vesicle
,
cranial neural crest
,
neural tube
|
rps29
|
|
tropicalis
|
NF stage 28
to
NF stage 29 and 30
|
otic vesicle
,
brain
,
somite
,
ventral blood island
,
pharyngeal arch
,
[+]
|
rps29
|
|
tropicalis
|
NF stage 35 and 36
to
NF stage 40
|
|
rps7
|
|
tropicalis
|
NF stage 3 (4-cell)
|
|
rps7
|
|
tropicalis
|
NF stage 10
|
dorsal
|
rps7
|
|
tropicalis
|
NF stage 14
to
NF stage 15
|
pre-chordal neural plate
,
chordal neural plate
,
neural plate
,
anterior neural fold
|
rps7
|
|
tropicalis
|
NF stage 22
|
somite
,
posterior neural tube
,
cranial neural crest
,
neural tube
|
rps7
|
|
tropicalis
|
NF stage 28
to
NF stage 40
|
brain
,
hindbrain
,
pharyngeal arch
,
mandibular arch
,
hyoid arch
,
[+]
|
rps19
|
|
tropicalis
|
NF stage 3 (4-cell)
|
animal blastomere
,
blastomere
|
rps19
|
|
tropicalis
|
NF stage 10
|
|
rps19
|
|
tropicalis
|
NF stage 14
to
NF stage 15
|
pre-chordal neural plate
,
chordal neural plate
,
neural plate
,
anterior neural fold
,
cranial neural crest
|
rps19
|
|
tropicalis
|
NF stage 22
|
mandibular crest
,
hyoid crest
,
branchial crest
,
optic vesicle
,
cranial neural crest
|
rps19
|
|
tropicalis
|
NF stage 28
to
NF stage 29 and 30
|
otic vesicle
,
heart
,
ventral blood island
,
eye
,
head
,
[+]
|
rps19
|
|
tropicalis
|
NF stage 35 and 36
to
NF stage 40
|
|
|
|
Fig. 3
rps genes are dynamically expressed in development. a Expression of all five rps genes examined was observed in the stage 10 gastrula, stage 16 neural folds, and migrating CNC at stage 20–22. b Each gene was widely detected in the developing head at later stages (28–40), including all the pharyngeal arches, brain, eyes and ears. rps17, 19 and 29 were also robustly detected in the ventral mesoderm, while rps7 was particularly defined in somites. With the exception of rps7, transcripts of all mRNAs were detected in the dorso-lateral plate mesodermal region where the pronephros and hypaxial muscle will form. c Red lines labeled a*, b* and c* in diagrams of stage 10 and 28 embryos represent the planes of section shown in a and b |
|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
rps14
|
|
tropicalis
|
NF stage 16
|
neural plate
,
anterior neural fold
|
rpl15
|
|
tropicalis
|
NF stage 16
|
|
tcof1
|
|
tropicalis
|
NF stage 18
|
anterior neural fold
|
rps29
|
|
tropicalis
|
NF stage 16
|
anterior neural fold
|
utp4
|
|
tropicalis
|
NF stage 16
|
pre-chordal neural plate
,
chordal neural plate
,
neural plate
,
anterior neural fold
|
sbds
|
|
tropicalis
|
NF stage 16
|
cranial neural crest
,
posterior
|
rbm28
|
|
tropicalis
|
NF stage 16
|
cranial neural crest
|
rps7
|
|
tropicalis
|
NF stage 16
|
pre-chordal neural plate
,
chordal neural plate
,
neural plate
,
anterior neural fold
|
rps19
|
|
tropicalis
|
NF stage 16
|
pre-chordal neural plate
,
chordal neural plate
,
anterior neural fold
,
cranial neural crest
|
rpl26
|
|
tropicalis
|
NF stage 16
|
neural plate
,
cranial neural crest
|
rpl35a
|
|
tropicalis
|
NF stage 16
|
pre-chordal neural plate
,
chordal neural plate
,
neural plate
,
neural plate border
|
rpl38
|
|
tropicalis
|
NF stage 16
|
pre-chordal neural plate
,
chordal neural plate
,
neural plate
,
cranial neural crest
|
|
|
Additional file 2: Comparison of digoxigenin labeled anti-sense and sense mRNA probes for each ribosomopathy gene in stage 16 embryos. Dorsal and anterior views are shown. Note the strong expression detected in the neural plate by the anti-sense mRNA probes while the control sense probed embryos remains unstained. (JPG 922 kb) |
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rps17 (ribosomal protein S17) gene expression in Xenopus tropicalis embryo, assayed via in situ hybridization, NF stage 28, lateral view, anterior left, dorsal up. |