|
Gene |
Clone |
Species |
Stages |
Anatomy |
rgn.L
|
|
laevis
|
NF stage 32
|
late proximal tubule
,
early proximal tubule
,
glomus
,
pronephric kidney
,
proximal tubule
,
[+]
|
rgn.L
|
|
laevis
|
NF stage 35 and 36
|
late proximal tubule
,
early proximal tubule
,
glomus
,
pronephric kidney
,
proximal tubule
,
[+]
|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
pax8
|
|
laevis
|
NF stage 32
|
pronephric nephrostome
,
late proximal tubule
,
early proximal tubule
,
glomus
,
pronephric kidney
,
[+]
|
pax2
|
|
laevis
|
NF stage 32
|
hindbrain
,
midbrain-hindbrain boundary
,
pronephric nephrostome
,
pronephric duct
,
post-anal gut
,
[+]
pronephric nephron
,
late proximal tubule
,
early distal tubule
,
early proximal tubule
,
late distal tubule
,
glomus
,
optic stalk
,
pronephric kidney
,
head mesenchyme
,
proximal tubule
,
distal tubule
,
proximal tubule branch
|
|
|
Figure 5. Impaired hspa9 expression in Xenopus laevis disturbs tubular pronephric development. A–F: Whole-mount smp30 ISH in MoC (A–C) and Mo-injected (D–F) tadpole embryos at the dose of 17 ng. G,H: At tail bud stage, smp30 expression is decreased upon Mo34 injection (34 ng). I–L: pax8 (I,J) and pax2 (K,L) ISH confirm the impaired development of the proximal pronephric tubule after reduced hspa9 expression. M–P: Double-immunofluorescence with 3G8 (red) and 4A6 (blue) antibodies (M,O) and corresponding drawings (N,P) illustrate a simplified pronephric tubule on the Mo17-injected side of the embryo.Download figure to PowerPoint |