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Fig. 8. Npnt is not required for pronephros or mesonephros formation. (A, B) Specification of pronephros occurs normally as shown by pax8 WISH in both wt (left panels) and xdm (right panels) at the tailbud stage (black arrowheads; white arrowheads show the otic vesicle). (C, D) At stage 40, xdm pax8 expression in pronephros (black arrowheads) is indistinguishable from wild type (white arrowheads mark hindbrain expression). (E, F) Dissected mesonephros from metamorphosing mutant tadpoles (F) is morphologically indistinguishable from wild type (E); the anterior is to the left. |
