|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
eomes
|
|
laevis
|
NF stage 32
to
NF stage 40
|
forebrain
,
telencephalon
,
olfactory bulb
,
lateral ganglionic eminence
,
pallium
,
[+]
|
nkx2-1
|
|
laevis
|
NF stage 32
to
NF stage 40
|
forebrain
,
telencephalon
,
pallium
,
dorsal pallium
,
lateral pallium
,
[+]
|
emx1
|
|
laevis
|
NF stage 32
to
NF stage 40
|
forebrain
,
telencephalon
,
olfactory bulb
,
lateral ganglionic eminence
,
pallium
,
[+]
|
dlc
|
|
laevis
|
NF stage 32
to
NF stage 40
|
forebrain
,
telencephalon
,
optic stalk
,
lateral ganglionic eminence
,
subpallium
,
[+]
|
|
|
Fig.5. Model summary of Xenopus embryonic forebrain subdivisions deduced from expression of x-Dll3, x-Nkx2.1, x-Emx1, x-Pax6 and x-Eomes. (A)
Schematic lateral view of an embryonic (compound stage 32/40) Xenopus brain with deduced subdivisions (orientation like in toto views in Fig. 1). Gene
expressions are colour-coded and migrated/migratory cells are indicated by little dots. The expression of each gene through the VZ, SVZ and MZ of the
neuroepithelium is recapitulated for each gene marker in each proposed subdivision. (B) Deduced subdivisions are indicated on a schematic hemi-section taken
from double-labelled embryos with the indicated probes. The subdivisions clearly emerge from the careful observation of labelling throughout the depth of the
neuroepithelium for each combination of genes. See Table 1 for abbreviations. |