| |
Fig. 1. RNA injection of Six6, Six3 or Xsix3 at low concentrations induces an increase in retina size. Vibratome sections of tailbud stage Xenopus embryos after whole-mount in situ hybridization. (A) Injection of 12.5 pg of Six6 RNA, or (B) 10 pg of Six3 RNA, or (C) 25 pg of Xsix3 RNA leads to enlargement of the neural retina. Overall eye shape and lens formation are not affected. (A,B) Xpax6 riboprobe. (C) Xrx riboprobe. rpe, retinal pigmented epithelium; nr, neural retina; ls, lens; is, injected side; nis, non-injected side. |
