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pax2xenopus   

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Experiment details for pax2

Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development.

Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development.

Gene Clone Species Stages Anatomy
pax2.L laevis NF stage 28 otic vesicle

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  Fig. 7. Gain of Pa2G4 disrupts gene expression in the otocyst. Otic genes are either reduced in intensity or undetected in the otocyst on the injected side (right image, red arrows, pink lineage tracer). Left image shows gene expression in the otocyst (black arrows) on the control side of the same embryo. Green arrows denote reduction in gene expression in the neural crest-derived branchial arches. Note that the otocysts are present in all cases. For all phenotypes in this figure, please see Table 2 for frequencies and the number of embryos analyzed.