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pax2xenopus   

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Experiment details for pax2

A restrictive role for Hedgehog signalling during otic specification in Xenopus.

A restrictive role for Hedgehog signalling during otic specification in Xenopus.

Gene Clone Species Stages Anatomy
pax2.L laevis NF stage 35 and 36 otic vesicle , brain , spinal cord , pronephric duct , central nervous system , [+]

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  Fig. 4. Effects of mHIP on XPtc1 expression and otic specification. Following injection of mHIP mRNA (750 pg) into one of two blastomeres, embryos were fixed at stage 38 (A) or stage 36 (B-G) and stained for expression of XPtc1 (A), Xdll-3 (B-E), or XPax-2 (F, G). mHIP-injected embryos (n 24) exhibit strongly reduced XPtc1 expression (74%; A). In parallel, ectopic vesicular structures (depicted by triangles) expressing Xdll-3 (27%, n 22) and XPax-2 (10%, n 31) were also observed in mHIP-injected embryos. is, injected side; nis, noninjected side.