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pax2xenopus   

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Experiment details for pax2



XPteg (Xenopus proximal tubules-expressed gene) is essential for pronephric mesoderm specification and tubulogenesis.

Gene Clone Species Stages Anatomy
pax2 xenopus NF stage 35 and 36 otic vesicle , brain , midbrain-hindbrain boundary , pronephric nephrostome , pronephric duct , [+]

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  Fig. 5. PDZ binding motif of XPteg is important for pronephros formation. PDZ-binding motif (STAM)-truncated XPteg (XPtegδSTAM) inhibited the expression of SMP30 and Pax2 but not that of Nephrin and MyoD. XPtegδSTAM RNA (500 pg) was injected in the presumptive pronephric region of embryos along with or without wild-type XPteg RNA and pronephric marker expression was analyzed by in situ hybridization.