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Gene/Clone | Species | Stage | Anatomy Item | Experimenter |
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nphs1 | xenopus |
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Experiment details for nphs1
Notch signaling, wt1 and foxc2 are key regulators of the podocyte gene regulatory network in Xenopus.Notch signaling, wt1 and foxc2 are key regulators of the podocyte gene regulatory network in Xenopus.
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Fig. 5. wt1 and foxc2 are required together for expression of podocyte genes. (A-I′) High magnification of transverse sections of whole-mount in situ hybridizations comparing the expression of podocyte genes wt1 (A,A′), tcf21 (B,B′), lmx1b (C,C′), mafb (D,D′), foxc2 (E,E′), ptpru (F,F′), nphs1 (G,G′), kirrel (H,H′) and nphs2 (I,I′) between wt1-MO1 plus foxc2-MO co-injected Xenopus embryos (A′-I′) and sibling controls (A-I) at stage 35. |