|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
foxc2
|
|
laevis
|
NF stage 35 and 36
|
branchial arch
,
tail bud
,
eye
,
glomus
,
pronephric kidney
,
[+]
|
kirrel1
|
|
laevis
|
NF stage 35 and 36
|
brain
,
heart
,
branchial arch
,
tail bud
,
exocrine pancreas
,
[+]
|
tcf21
|
|
laevis
|
NF stage 35 and 36
|
branchial arch
,
lateral plate mesoderm
,
glomus
,
pronephric kidney
,
podocyte
|
wt1
|
|
laevis
|
NF stage 35 and 36
|
heart
,
intermediate mesoderm
,
glomus
,
pronephric kidney
,
podocyte
|
nphs2
|
|
laevis
|
NF stage 35 and 36
|
otic placode
,
glomus
,
pronephric kidney
,
neural tube
,
podocyte
|
lmx1b.1
|
|
laevis
|
NF stage 35 and 36
|
ectoderm
,
eye
,
otic placode
,
glomus
,
pronephric kidney
,
[+]
|
ptpru
|
|
laevis
|
NF stage 35 and 36
|
brain
,
forebrain
,
eye
,
glomus
,
pronephric kidney
,
[+]
|
mafb
|
|
laevis
|
NF stage 35 and 36
|
lens
,
hindbrain
,
somite
,
eye
,
late proximal tubule
,
[+]
|
|
|
Fig. 1. Spatiotemporal expression of podocyte genes. (A-A′) Schematics depicting the glomus (black) in whole Xenopus embryos (A) and in transverse section at low (A′) and high (A′) magnification at stage 35. (B-J′) In situ hybridization of podocyte transcription factors wt1 (B-B′), foxc2 (C-C′), tcf21 (D-D′), mafb (E-E′) and lmx1b (F-F′) and of markers of podocyte differentiation kirrel (G-G′), nphs1 (H-H′), ptpru (I-I′) and nphs2 (J-J′) at stage 35 in whole-mounts (B-J) and transverse sections (B′-J′). (K) Temporal profile of podocyte gene expression in the glomus. en, endoderm; g, pronephric glomus; lpm, lateral plate mesoderm; no, notochord; nt, neural tube; so, somites; t, pronephric tubules. |