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Khokha MK et al. (2005) AssayDepletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures.
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| Figure 3. FCN Morphants Have a Catastrophic Loss in Dorsal DevelopmentAll panels are dorsal views with anterior to the top of st 14–15 neurula embryos. Expression of multiple dorsal markers (sox2 [A–D], sox3 [E–H], myf5 [I–L], myoD [M–P], shh [Q–T], and xnot [U–X]) are shown in uninjected sibling embryos (A, C, E, G, I, K, M, O, Q, S, U, and W) and follistatin, chordin, and noggin (FCN) triple morphants (B, F, J, N, R, and V) as well as β-catenin morphants (D, H, L, P, T, and X) for comparison. |