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nogxenopus   

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Experiment details for nog

Khokha MK et al. (2005) Assay

Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures.

Gene Clone Species Stages Anatomy
nog tropicalis NF stage 8 dorsal marginal zone
nog tropicalis NF stage 9 dorsal marginal zone
nog tropicalis NF stage 10.5 involuted dorsal mesoderm
nog tropicalis NF stage 11 involuted dorsal mesoderm

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  Figure 1. BMP Antagonists Are Expressed in Spemann’s OrganizerBlastula and gastrula embryos were bisected, stained, and then cleared to visualize expression of follistatin (A, F, K, and P), chordin (B, G, L, and Q), noggin (C, H, M, and R), xnr3 (D, I, N, and S), and cerberus (E, J, O, and T) at midblastula (A–E), late blastula (F–J), early gastrula (K–O), and midgastrula (P–T). Dorsal is to the right with the animal pole toward the top of the figure. St = stage.