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nkx2-5xenopus   

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Experiment details for nkx2-5

Zhang C et al. (2005) Assay

SOX7 and SOX18 are essential for cardiogenesis in Xenopus.

Gene Clone Species Stages Anatomy
nkx2-5.L laevis NF stage 25 to NF stage 29 and 30 mesoderm , heart , ventral

  Suppl Fig 1. Fertilized eggs were injected with either SOX18(delta)C-VP16myc (B), SOX7(delta)C-VP16myc (C), SOX18-GFP (E), or SOX7-GFP (F) RNAs (0.5 ng/embryo). At stages between 25 (A-C) and 30 (D-F) the embryos were stained in situ for Nkx2.5. Compared to uninjected controls (A,D), both GFP and DC-VP16 myc forms of SOX7 and SOX18 induced an apparent increase in the extent and intensity of the Nkx2.5 expression domain.