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nbl1xenopus   

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Experiment details for nbl1

Xenopus Dan, a member of the Dan gene family of BMP antagonists, is expressed in derivatives of the cranial and trunk neural ...

Xenopus Dan, a member of the Dan gene family of BMP antagonists, is expressed in derivatives of the cranial and trunk neural crest.

Gene Clone Species Stages Anatomy
nbl1.L laevis NF stage 25 midbrain-hindbrain boundary , mandibular crest , otic placode , trunk neural crest , cranial neural crest
nbl1.L laevis NF stage 29 and 30 to NF stage 37 and 38 fin , otic vesicle , brain , forebrain , midbrain , [+]

  Fig. 2. Localization of XDan expression by whole-mount in situ hybridization. Except in (A,B,I,L) embryos were cleared with benzyl benzoate/benzyl alcohol. (A,B) Localization of maternal XDan transcripts (in each panel the top pair was probed for XDan while the bottom pair was probed with a sense control to access background staining). (A) Maternal XDan transcripts in stage VI oocytes. (B) Maternal transcripts in stage 3 embryos. (C) Lateral view of stage 25 embryos. (D) Dorsal view of stage 25 embryos. (E) Lateral view of stage 30 embryos. (F) Close up of stage 30 embryo showing XDan expression in derivatives of the cranial neural crest. (G) Horizontal section through the head and foregut of stage 30 embryo. Note that XDan expression is apparent in both superficial and underlying levels of the mandibular, hyoid, and branchial arches. (H) XDan expression in the fin mesenchyme of stage 38 embryo. (I) Lateral view of XDan expression in uncleared stage 38 embryo illustrating weak expression in the chevron-shaped ventral migration pathways of trunk neural crest. (J) Lateral view of XDan expression in the head of stage 38 embryo. (K) Horizontal section passing directly through the eye of a stage 38 embryo. (L) Dorsal view of stage 38 trunk. b, Brain; br, branchial arches; ev, eye vesicle; ha, hyoid arch; m, midbrain; ma, mandibular arch; mcs, mandibular crest segment; mh, midbrain–hindbrain boundary; ov, otic vesicle; t, trunk neural crest.