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Figure 6. Spemann’s Organizer Is Specified in FCN MorphantsAll panels are vegetal views of early gastrula embryos (st 10.5 [A–T]) or midgastrula (st 11 [U–X]) with dorsal to the right in embryos where dorsal can be distinguished. Expression of multiple mesodermal markers (brachyury [xbra] [A–D], goosecoid [gsc] [E–H], xnr3 [I–L], siamois [M–P], vent2 [Q–T], and myf5 [U–X]) are shown in uninjected sibling embryos (A, C, E, G, I, K, M, O, Q, S, U, and W) and FCN triple morphants (B, F, J, N, R, and V) as well as β-catenin morphants (D, H, L, P, T, and X) for comparison. |
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Figure 3. FCN Morphants Have a Catastrophic Loss in Dorsal DevelopmentAll panels are dorsal views with anterior to the top of st 14–15 neurula embryos. Expression of multiple dorsal markers (sox2 [A–D], sox3 [E–H], myf5 [I–L], myoD [M–P], shh [Q–T], and xnot [U–X]) are shown in uninjected sibling embryos (A, C, E, G, I, K, M, O, Q, S, U, and W) and follistatin, chordin, and noggin (FCN) triple morphants (B, F, J, N, R, and V) as well as β-catenin morphants (D, H, L, P, T, and X) for comparison. |
