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mycxenopus   

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Experiment details for myc

Newman CS and Krieg PA (1999) Assay

Alternative splicing and embryonic expression of the Xenopus mad4 bHLH gene.

Gene Clone Species Stages Anatomy
myc.S laevis NF stage 11 animal hemisphere , blastocoel roof , animal pole
myc.S laevis NF stage 13 to NF stage 14 cement gland primordium , circumblastoporal collar , cranial neural crest
myc.S laevis NF stage 24 to NF stage 25 mandibular crest , hyoid crest , branchial crest , optic vesicle , cranial neural crest , [+]
myc.S laevis NF stage 28 brain , forebrain , midbrain , midbrain-hindbrain boundary , stomodeal-hypophyseal primordium , [+]
myc.S laevis NF stage 29 and 30 pancreas , foregut

  Fig. 6. Developmental expression pattern of the c-myc gene. A: Anterior view of an early neurula stage embryo showing c-myc expression in the cranial neural crest (arrowheads) and future cement gland (arrow). B: Posterior view of the same embryo shown in (A). Note strong expression in the cells immediately surrounding the newly closed blasto- pore. C: Lateral view of an early tailbud stage embryo showing c-myc staining in the neural crest entering the posterior pharyngeal arches (arrows), as well as in the eye (arrowhead) and the brain (white arrowhead). D: Lateral view of a mid tailbud stage embryo. c-myc expression is retained in the pharyngeal arches, most strongly in arch 2 (short arrow). Other domains of expression include the eye (long arrow), floor of the pharynx (small arrowhead), and cells of the first pharyngeal arch (large arrowhead). E: Lateral view of a tadpole stage embryo. Note expression in the pancreatic anlage (arrow), as well as in cells adjacent to the liver (arrowhead). F: Sagital section through a gastrula stage embryo stained for c-myc. Expression is strongest in the animal pole (arrowhead). G: Cross-section through an early neurula stage embryo. c-myc expres- sion is strongest in the intermediate mesoderm (large arrowhead) and the embryonic ectoderm (arrow). Paraxial mesoderm is also weakly positive (small arrowhead). H: Cross-section of a mid tailbud embryo. The future liver is positive for the c-myc gene. I: Cross-section of a mid tailbud stage embryo. c-myc expression is strong in the peripheral optic cup (arrow- head) and dorsal brain (arrow). J: Cross-section of a mid tailbud stage embryo. Note expression in dorsal somite (arrowhead), as well as in the dorsal gut (arrow).