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Fig. 3. Wnt/β-catenin signaling in the PSM. (A–J) The neurula stage embryos were stained by whole-mount in situ hybridization for Xwnt8 (A, B, arrowhead), Dkk1 (C, D, arrow), Xwnt8 and Dkk1 (E, F, arrowhead indicates XWnt8 and arrow indicates DKK1), Xwnt8 and Thy (G, H, arrowhead indicates XWn8 and arrow indicates Thy), or Mespo and Thy (I, J, arrowhead indicates Mespo and arrow indicates Thy). Embryos in panels A, C, E, G and I are oriented with anterior to the left and shown in lateral views. Embryos in panels B, D, F, H and J show posterior–dorsal view. (K) Schematic diagram (adapted from Kim et al., 2000) illustrates gene expression patterns related to somite formation in the PSM of Xenopus embryos. |
