Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Search Criteria
Gene/CloneSpeciesStageAnatomy ItemExperimenter
lhx1xenopus   

Too many results?Too few results?

Experiment details for lhx1

Wallingford JB et al. (1998) Assay

Precocious expression of the Wilms' tumor gene xWT1 inhibits embryonic kidney development in Xenopus laevis.

Gene Clone Species Stages Anatomy
lhx1.L laevis NF stage 20 intermediate mesoderm , pronephric mesenchyme

  FIG. 5. xWT1 expression disrupts early events in pronephric specification. Expression of Xlim-1, an early molecular marker for the pronephros, was detected at stage 20 by in situ hybridization (dark purple in all panels) and b-galactosidase was detected with X-Gal (light blue/green in B and D). (A and B) Opposite sides of an embryo injected on one side with of b-galactosidase mRNA. Xlim-1 expression is strong on both the uninjected (A) and injected (B) sides. (C and D) Opposite sides of an embryo injected on one side with xWT1-KTS (1b-galactosidase mRNA). Xlim-1 expression is normal on the uninjected side (C), while expression is dramatically reduced on the injected side (D). The result indicates that ectopic xWT1 mRNA expression inhibits pronephric development at a very early stage.